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dc.contributor.authorChao, Joshua T
dc.contributor.authorBiggs, Manus JP
dc.contributor.authorPandit, Abhay S
dc.date.accessioned2018-09-20T16:03:03Z
dc.date.available2018-09-20T16:03:03Z
dc.date.issued2014-08-22
dc.identifier.citationChao, Joshua T; Biggs, Manus JP; Pandit, Abhay S (2014). Diatoms: a biotemplating approach to fabricating drug delivery reservoirs. Expert Opinion on Drug Delivery 11 (11), 1687-1695
dc.identifier.issn1742-5247,1744-7593
dc.identifier.urihttp://hdl.handle.net/10379/10748
dc.description.abstractBiotemplating is a rapidly expanding subfield that utilizes nature-inspired systems and structures to create novel functional materials, and it is through these methods that the limitations of current engineering practices may be advanced. The diatom is an exceptional template for drug delivery applications, owing largely to its highly-ordered pores, large surface area, species-specific architecture, and flexibility for surface modifications. Diatoms have been studied in a wide range of biomedical applications and their potential as the next frontier of drug delivery has yet to be fully exploited. In this editorial, the authors aim to review the use of diatoms in the delivery of poorly water-soluble drugs as reported in the literature, discuss the progress and advancements that have been made thus far, identify the shortcomings and limitations in the field, and, lastly, present their expert opinion and convey the future outlook on biotemplating approaches for drug delivery.
dc.publisherInforma Healthcare
dc.relation.ispartofExpert Opinion on Drug Delivery
dc.subjectbiotemplating
dc.subjectdiatom
dc.subjectfrustule
dc.subjectmarine resources
dc.subjectskeleton
dc.subjectpreserving reactive conversion
dc.subjectsilica microparticles
dc.subjectthalassiosira-weissflogii
dc.subjectgold nanostructures
dc.subjectoral delivery
dc.subjectbiosilica
dc.subjectassemblies
dc.subjectfrustules
dc.subjectmicroshells
dc.subjectbiomimetics
dc.titleDiatoms: a biotemplating approach to fabricating drug delivery reservoirs
dc.typeArticle
dc.identifier.doi10.1517/17425247.2014.935336
dc.local.publishedsourcehttp://www.tandfonline.com/doi/pdf/10.1517/17425247.2014.935336?needAccess=true
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