Now showing items 1-10 of 120
Migrastatin analogues inhibit canine mammary cancer cell migration and invasion
(Public Library of Science (PLoS), 2013-10-08)
Background: Cancer spread to other organs is the main cause of death of oncological patients. Migration of cancer cells from a primary tumour is the crucial step in the complex process of metastasis, therefore blocking ...
Micrornas as prognostic indicators and therapeutic targets: potential effect on breast cancer management
(American Association for Cancer Research (AACR), 2008-01-15)
The discovery of microRNAs (miRNA) as novel modulators of gene expression has resulted in a rapidly expanding repertoire of molecules in this family, as reflected in the concomitant expansion of scientific literature. ...
Early growth response-1 is a regulator of dr5-induced apoptosis in colon cancer cells
(Springer Nature, 2010-01-19)
A gene regulatory network underlying the formation of pre-placodal ectoderm in xenopus laevis
(Springer Nature, 2018-07-16)
Background: The neural plate border ectoderm gives rise to key developmental structures during embryogenesis, including the neural crest and the preplacodal ectoderm. Many sensory organs and ganglia of vertebrates develop ...
Overexpression of wnt5a in mouse epidermis causes no psoriasis phenotype but an impairment of hair follicle anagen development
Increased Wnt5a expression has been observed in psoriatic plaques. However, whether Wnt5a overexpression directly causes psoriasis is unknown. In this study, we generated transgenic (TG) mice with epidermal Wnt5a overexpression ...
Cutting edge: il-7 regulates the peripheral pool of adult ror + lymphoid tissue inducer cells
(The American Association of Immunologists, 2009-07-27)
During fetal life, CD4(+)CD3(-) lymphoid tissue inducer (LTi) cells are required for lymph node and Peyer's patch development in mice. In adult animals, CD4(+) CD3(-) cells are found in low numbers in lymphoid organs. ...
Single nucleotide polymorphisms within the bovine dlk1-dio3 imprinted domain are associated with economically important production traits in cattle
(Oxford University Press (OUP), 2010-09-03)
Previous studies show that DNA sequence variation within the mammalian DLK1-DIO3 imprinted domain influences production traits in domestic livestock, most notably the ovine callipyge phenotype. We assessed genotype-phenotype ...
Thiamine plays a critical role in the acid tolerance of listeria monocytogenes
(Oxford University Press (OUP), 2011-11-14)
Understanding the molecular basis of acid tolerance in the food-borne pathogen Listeria monocytogenes is important as this property contributes to survival in the food-chain and enhances survival within infected hosts. The ...
Fluorescent labeling of nasba amplified tmrna molecules for microarray applications
(Springer Nature, 2009-01-01)
Background: Here we present a novel promising microbial diagnostic method that combines the sensitivity of Nucleic Acid Sequence Based Amplification (NASBA) with the high information content of microarray technology for ...