Browsing Externally hosted open access publications with University of Galway authors (2) by Subject "xbp1 messenger-rna"
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Drugging the unfolded protein response in acute leukemias
(Springer Nature, 2015-07-16)The unfolded protein response (UPR), an endoplasmic reticulum (ER) stress-induced signaling cascade, is mediated by three major stress sensors IRE-1 alpha, PERK, and ATF6 alpha. Studies described the UPR as a critical ...