Browsing Externally hosted open access publications with University of Galway authors (2) by Subject "mytilus-edulis"
Now showing items 1-12 of 12
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A mussel tissue certified reference material for multiple phycotoxins. part 1: design and preparation
(Springer Nature, 2011-03-17)The development of multi-analyte methods for lipophilic shellfish toxins based on liquid chromatography-mass spectrometry permits rapid screening and analysis of samples for a wide variety of toxins in a single run. Validated ... -
Alkene 1,2-difunctionalization via radical alkenyl migration
(Wiley-Blackwell, 2017-11-22)The previously accepted structure of the marine toxin azaspiracid-3 is revised based upon an original convergent and stereoselective total synthesis of the natural product. The development of a structural revision hypothesis, ... -
Comparative effects of the marine algal toxins azaspiracid-1, -2, and -3 on jurkat t lymphocyte cells
(American Chemical Society (ACS), 2012-03-19)Azaspiracids (AZA) are polyether marine toxins of dinoflagellate origin that accumulate in shellfish and represent an emerging human health risk. Although monitored and regulated in many European and Asian countries, there ... -
Formation of azaspiracids-3, -4, -6, and -9 via decarboxylation of carboxyazaspiracid metabolites from shellfish
(American Chemical Society (ACS), 2009-01-14)The azaspiracid (AZA) class of phycotoxins has been responsible for extended closures of shellfisheries in various locations around Europe, where levels of AZA1-3 are regulated in shellfish. Since their discovery in 1995, ... -
Improved isolation procedure for azaspiracids from shellfish, structural elucidation of azaspiracid-6, and stability studies
(American Chemical Society (ACS), 2012-03-14)Azaspiracids are a group of lipophilic polyether toxins produced by the small dinoflagellate Azadinium spinosum. They may accumulate in shellfish and can result in illnesses when consumed by humans. Research into analytical ... -
Production and isolation of azaspiracid-1 and -2 from azadinium spinosum culture in pilot scale photobioreactors
(MDPI AG, 2012-06-13)Azaspiracid (AZA) poisoning has been reported following consumption of contaminated shellfish, and is of human health concern. Hence, it is important to have sustainable amounts of the causative toxins available for ... -
Quantitative analysis of azaspiracids in azadinium spinosum cultures
(Springer Nature, 2012-02-26)Azaspiracids (AZAs) are secondary metabolites of Azadinium spinosum that can accumulate in shellfish and cause food poisoning when consumed. We describe here an analytical procedure for the determination of AZAs in cultures ... -
Structure elucidation and in vitro toxicity of new azaspiracids isolated from the marine dinoflagellate azadinium poporum
(MDPI AG, 2015-10-30)Two strains of Azadinium poporum, one from the Korean West coast and the other from the North Sea, were mass cultured for isolation of new azaspiracids. Approximately 0.9 mg of pure AZA-36 (1) and 1.3 mg of pure AZA-37 (2) ... -
The preparation of certified calibration solutions for azaspiracid-1, -2, and -3, potent marine biotoxins found in shellfish
(Springer Nature, 2010-09-09)The production and certification of a series of azaspiracid (AZA) calibration solution reference materials is described. Azaspiracids were isolated from contaminated mussels, purified by preparative liquid chromatography ... -
The role of azadinium spinosum (dinophyceae) in the production of azaspiracid shellfish poisoning in mussels
(Elsevier BV, 2011-09-01)