Browsing Externally hosted open access publications with University of Galway authors (2) by Subject "abnormalities"
Now showing items 1-11 of 11
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Applying neuroimaging to detect neuroanatomical dysconnectivity in psychosis
(Cambridge University Press (CUP), 2015-02-12)This editorial discusses the application of a novel brain imaging analysis technique in the assessment of neuroanatomical dysconnectivity in psychotic illnesses. There has long been a clinical interest in psychosis as a ... -
Corpus callosum area in patients with bipolar disorder with and without psychotic features: an international multicentre study
(Joule Inc., 2015-09-01)Background Previous studies have reported MRI abnormalities of the corpus callosum (CC) in patients with bipolar disorder (BD), although only a few studies have directly compared callosal areas in psychotic versus nonpsychotic ... -
Effects of risk for bipolar disorder on brain function: a twin and family study
(Elsevier BV, 2017-05-01) -
Home detection of freezing of gait using support vector machines through a single waist-worn triaxial accelerometer
(Public Library of Science (PLoS), 2017-02-15)Among Parkinson's disease (PD) symptoms, freezing of gait (FoG) is one of the most debilitating. To assess FoG, current clinical practice mostly employs repeated evaluations over weeks and months based on questionnaires, ... -
In vivo imaging of tau pathology using magnetic resonance imaging textural analysis
(Frontiers Media SA, 2017-11-06)Background: Non-invasive characterization of the pathological features of Alzheimer's disease (AD) could enhance patient management and the development of therapeutic strategies. Magnetic resonance imaging texture analysis ... -
Meta-analysis of regional white matter volume in bipolar disorder with replication in an independent sample using coordinates, t-maps, and individual mri data
(Elsevier BV, 2017-11-01)Converging evidence suggests that bipolar disorder (BD) is associated with white matter (WM) abnormalities. Meta-analyses of voxel based morphometry (VBM) data is commonly performed using published coordinates, however ... -
Ten-year follow-up of spa-related oligoarthritis involving the knee: the presence of psoriasis but not hla-b27 or baseline mri bone oedema predicts outcome
(Oxford University Press (OUP), 2012-02-10)Objective. Bone marrow oedema (BMO) and HLA-B27 are poor prognostic factors in axial SpA, and psoriasis is a poor prognostic factor in small-joint polyarthropathy. The aim of this study was to investigate the influence of ... -
The effects of blood–brain barrier disruption on glial cell function in multiple sclerosis: figure 1
(Portland Press Ltd., 2009-02-01)Dysfunction of the BBB (blood-brain barrier) is a major hallmark of MS (multiple sclerosis). Studies in our laboratories over the last decade have shown that increased 131313 permeability is associated with decreased ... -
The impact of cacna1c gene, and its epistasis with znf804a, on white matter microstructure in health, schizophrenia and bipolar disorder1
(Wiley-Blackwell, 2016-11-29)Genome-wide studies have identified allele A (adenine) of single nucleotide polymorphism (SNP) rs1006737 of the calcium-channel CACNA1C gene as a risk factor for both schizophrenia (SZ) and bipolar disorder (BD) as well ... -
White matter microstructural impairments and genetic liability to familial bipolar i disorder
(Royal College of Psychiatrists, 2009-05-28)Background Subtle abnormalities in frontal white matter have been reported in bipolar disorder. Aims To assess whether impaired integrity of white matter tracts is associated with bipolar disorder and genetic liability for ...