Browsing by Author "Curran, C."
Now showing items 1-6 of 6
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Breast cancer subtype discordance: impact on post-recurrence survival and potential treatment options
McAnena, Peter F.; Brown, James AL; Ramli, A.; Curran, C.; Malone, C.; McLaughlin, R.; Barry, K.; JAL, Brown; Kerin, M. J. (Springer Nature, 2018-02-20)Background: Recent studies have shown that breast cancer subtype can change from the primary tumour to the recurrence. Discordance between primary and recurrent breast cancer has implications for further treatment and ... -
Correction to: breast cancer subtype discordance: impact on post-recurrence survival and potential treatment options
McAnena, Peter F.; McGuire, Andrew; Ramli, A.; Curran, C.; Malone, C.; McLaughlin, R.; Barry, K.; Brown, James A. L.; Kerin, M. J. (Springer Nature, 2018-03-13) -
Erratum to: evaluation of variants in the chek2, brip1 and palb2 genes in an irish breast cancer cohort
McInerney, N. M.; Miller, N.; Rowan, A.; Colleran, G.; Barclay, E.; Curran, C.; Kerin, M. J.; Tomlinson, I. P.; Sawyer, E. (Springer Nature, 2011-03-29) -
Evaluation of variants in the chek2, brip1 and palb2 genes in an irish breast cancer cohort
McInerney, N. M.; Miller, N.; Rowan, A.; Colleran, G.; Barclay, E.; Curran, C.; Kerin, M. J.; Tomlinson, I. P.; Sawyer, E. (Springer Nature, 2009-09-18)It has been proposed that rare variants within the double strand break repair genes CHEK2, BRIP1 and PALB2 predispose to breast cancer. The aim of this study was to evaluate the prevalence of these variants in an Irish ... -
Potential role of mesenchymal stem cells (MSCs) in the breast tumour microenvironment: stimulation of epithelial to mesenchymal transition (EMT)
Martin, F. T.; Dwyer, Róisín M.; Kelly, J.; Khan, S.; Murphy, J. M.; Curran, C.; Miller, N.; Hennessy, E.; Dockery, P.; Barry, F. P.; O'Brien, T.; Kerin, Michael J. (Springer, 2010-01-20)Bone marrow-derived mesenchymal stem cells (MSCs) are known to specifically migrate to and engraft at tumour sites. Understanding interactions between cancer cells and MSCs has become fundamental to determining whether ... -
Top2a amplification in the absence of that of her-2/neu: toward individualization of chemotherapeutic practice in breast cancer
Glynn, R. W.; Mahon, S.; Curran, C.; Callagy, G.; Miller, N.; Kerin, M. J. (Alphamed Press, 2011-06-24)Primary objective. To investigate the relationship between human epidermal growth factor receptor (HER)-2/neu and the gene encoding topoisomerase II alpha (TOP2A) in breast cancer, while elucidating their association with ...