Browsing by Author "Avril, Tony"

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    • Dual ire1 rnase functions dictate glioblastoma development 

      Lhomond, Stéphanie; Avril, Tony; Dejeans, Nicolas; Voutetakis, Konstantinos; Doultsinos, Dimitrios; McMahon, Mari; Pineau, Raphaël; Obacz, Joanna; Papadodima, Olga; Jouan, Florence; Bourien, Heloise; Logotheti, Marianthi; Jégou, Gwénaële; Pallares‐Lupon, Néstor; Schmit, Kathleen; Le Reste, Pierre‐Jean; Etcheverry, Amandine; Mosser, Jean; Barroso, Kim; Vauléon, Elodie; Maurel, Marion; Samali, Afshin; Patterson, John B; Pluquet, Olivier; Hetz, Claudio; Quillien, Véronique; Chatziioannou, Aristotelis; Chevet, Eric (EMBO, 2018-01-08)
      Proteostasis imbalance is emerging as a major hallmark of cancer, driving tumor aggressiveness. Evidence suggests that the endoplasmic reticulum (ER), a major site for protein folding and quality control, plays a critical ...