Browsing by Subject "vibrating mesh nebulizer"
Now showing items 1-2 of 2
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Early-stage development of novel cyclodextrin-sirna nanocomplexes allows for successful postnebulization transfection of bronchial epithelial cells
(Mary Ann Liebert Inc, 2014-12-01)Background: Successful delivery of small interfering RNA (siRNA) to the lungs remains hampered by poor intracellular delivery, vector-mediated cytotoxicity, and an inability to withstand nebulization. Recently, a novel ... -
Optimization and dose estimation of aerosol delivery to non-human primates
(Mary Ann Liebert Inc, 2016-06-01)Background: In pre-clinical animal studies, the uniformity of dosing across subjects and routes of administration is a crucial requirement. In preparation for a study in which aerosolized live-attenuated measles virus ...