Browsing by Subject "somatic instability"
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Mutsβ abundance and msh3 atp hydrolysis activity are important drivers of ctg•cag repeat expansions (Oxford University Press (OUP), 2017-07-21)CTG circle CAG repeat expansions cause at least twelve inherited neurological diseases. Expansions require the presence, not the absence, of the mismatch repair protein MutS beta (Msh2-Msh3 heterodimer). To evaluate ...