Browsing by Subject "pregnancy"
Now showing items 1-20 of 38
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A core outcome set for studies evaluating the effectiveness of prepregnancy care for women with pregestational diabetes
(Springer Nature, 2017-04-13)Aims/hypothesis The aim of this study was to develop a core outcome set (COS) for trials and other studies evaluating the effectiveness of prepregnancy care for women with pregestational (pre-existing) diabetes mellitus. Methods ... -
Adrb3 adrenergic receptor is a key regulator of human myometrial apoptosis and inflammation during chorioamnionitis1
(Oxford University Press (OUP), 2008-03-01)The pathophysiology underlying preterm labor triggered by inflammatory conditions such as chorioamnionitis remains largely unclear. It has already been suggested that beta-3 adrenergic (ADRB3) agonists might be of interest ... -
An evaluation of cro� myaction community lifestyle modification programme compared to standard care to reduce progression to diabetes/pre-diabetes in women with prior gestational diabetes mellitus (gdm): study protocol for a randomised controlled trial
(Springer Nature, 2013-01-01)Background: Universal screening using the International Association of Diabetes and Pregnancy Study Groups (IADPSG) criteria has identified a prevalence of gestational diabetes mellitus (GDM) of 12.4% in women living in ... -
Assessment of the consequences of gestational SSRI antidepressant exposure in the rat
(NUI Galway, 2019-10-08)Although the most common psychotropic drugs prescribed in pregnancy are selective serotonin reuptake inhibitor (SSRI) antidepressants, their health impact on the resultant offspring is largely unknown due to the ethical ... -
Atlantic dip: high prevalence of abnormal glucose tolerance post partum is reduced by breast-feeding in women with prior gestational diabetes mellitus
(BioScientifica, 2011-09-21)Objective: Gestational diabetes (GDM) is associated with adverse fetal and maternal outcomes, and identifies women at risk of future type 2 diabetes mellitus (T2DM). Breast-feeding may improve post partum maternal glucose ... -
Atlantic dip: simplifying the follow-up of women with previous gestational diabetes
(BioScientifica, 2013-10-03)Objective: Previous gestational diabetes (GDM) is associated with a significant lifetime risk of type 2 diabetes. In this study, we assessed the performance of HbA1c and fasting plasma glucose (FPG) measurements against ... -
Atlantic-dip: prevalence of metabolic syndrome and insulin resistance in women with previous gestational diabetes mellitus by international association of diabetes in pregnancy study groups criteria
(Springer Nature, 2014-07-08)Women with previous gestational diabetes (GDM) are a high-risk group for future development of diabetes, metabolic syndrome, and cardiovascular disease. The new International Association of Diabetes in Pregnancy Study ... -
Comparing type 1 and type 2 diabetes in pregnancy- similar conditions or is a separate approach required?
(Springer Nature, 2015-03-27)Background: Pregnancy in women with type 1 (T1DM) or type 2 diabetes (T2DM) is associated with increased risk. These conditions are managed similarly during pregnancy, and compared directly in analyses, however they affect ... -
Correlates of poor mental health in early pregnancy in obese european women
(Springer Nature, 2017-12-01)Background: Depression during pregnancy is associated with higher maternal morbidity and mortality, and subsequent possible adverse effects on the cognitive, emotional and behavioral development of the child. The aim of ... -
Dali: vitamin d and lifestyle intervention for gestational diabetes mellitus (gdm) prevention: an european multicentre, randomised trial – study protocol
(Springer Nature, 2013-07-05)Background: Gestational diabetes mellitus (GDM) is an increasing problem world-wide. Lifestyle interventions and/or vitamin D supplementation might help prevent GDM in some women. Methods/design: Pregnant women at risk of ... -
Effectiveness of prepregnancy care for women with pregestational diabetes mellitus: protocol for a systematic review of the literature and identification of a core outcomes set using a delphi survey
(Springer Nature, 2015-08-14)Background: Women with pregnancy complicated by pregestational diabetes experience increased rates of adverse pregnancy outcomes. Prepregnancy care is the targeted support and additional care offered to those women who are ... -
Effects and mechanisms of action of sildenafil citrate in human chorionic arteries
(Springer Nature, 2009-01-01)Objectives: Sildenafil citrate, a specific phosphodiesterase-5 inhibitor, is increasingly used for pulmonary hypertension in pregnancy. Sildenafil is also emerging as a potential candidate for the treatment of intra-uterine ... -
Epidemiology of gestational diabetes mellitus according to iadpsg/who 2013 criteria among obese pregnant women in europe
(Springer Nature, 2017-07-12)Aims/hypothesis Accurate prevalence estimates for gestational diabetes mellitus (GDM) among pregnant women in Europe are lacking owing to the use of a multitude of diagnostic criteria and screening strategies in both ... -
Expression of prothrombin and protease activated receptors in human myometrium during pregnancy and labor1
(Oxford University Press (OUP), 2008-01-01)As thrombin is proposed to be involved in stimulating myometrial contractility during labor and preterm labor, we aimed to investigate the expression of prothrombin (F7), the precursor of thrombin, its receptors, the ... -
Ghrelin in the human myometrium
(Springer Nature, 2010-01-01)Background: Ghrelin is a 28-amino acid octanolyated peptide, synthesised primarily in the stomach. It stimulates growth hormone release, food intake and exhibits many other diverse effects. Our group have previously ... -
Hellp syndrome: a case report with guidelines for diagnosis and management
(Oxford University Press (OUP), 1991-01-01)A 25-yr-old patient with a twin pregnancy of 34 weeks gestation developed HELLP syndrome and required urgent delivery by Caesarean section. Before operation, a central venous catheter and urinary catheter were inserted, ... -
Human uterine lower segment myometrial cell and nuclear volume at term: influence of maternal age
(Wiley-Blackwell, 2014-09-29)Little is known about the cytoarchitecture of human myometrial cells in pregnancy, and whether or not this may be influenced by maternal characteristics such as age, parity and body mass index (BMI). The aim of this study ... -
Increasing trends in atonic postpartum haemorrhage in ireland: an 11-year population-based cohort study
(Wiley-Blackwell, 2011-12-13)Objective To derive nationally representative incidence rates of postpartum haemorrhage (PPH), and to investigate trends associated with method of delivery, blood transfusion and morbidly adherent placenta (accreta, percreta ... -
Is a motivational interviewing based lifestyle intervention for obese pregnant women across europe implemented as planned? process evaluation of the dali study
(Springer Nature, 2017-09-07)Background: Process evaluation is an essential part of designing and assessing complex interventions. The vitamin D and lifestyle intervention study (DALI) study is testing different strategies to prevent development of ... -
Obesity prevention during early life: Developing the evidence base to maximise the effectiveness of interventions delivered by health professionals
(NUI Galway, 2020-05-10)Background: Childhood obesity is a global public health challenge. Research priorities have not been established for obesity prevention research across childhood, however. Coproduction of research priorities leads to ...