Browsing by Subject "oncolytic adenoviruses"

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    • Advances in mesenchymal stem cell-mediated gene therapy for cancer 

      Dwyer, Róisín M.; Khan, Sonja; Barry, Frank P; O'Brien, Timothy; Kerin, Michael J (Springer Nature, 2010-01-01)
      Mesenchymal stem cells have a natural tropism for tumours and their metastases, and are also considered immunoprivileged. This remarkable combination of properties has formed the basis for many studies investigating their ...

    • Mesenchymal stem cells expressing trail lead to tumour growth inhibition in an experimental lung cancer model 

      Mohr, Andrea; Lyons, Mark; Deedigan, Laura; Harte, Tina; Shaw, Georgina; Howard, Linda; Barry, Frank; O'Brien, Tim; Zwacka, Ralf (Wiley-Blackwell, 2008-03-29)
      Lung cancer is a major public health problem in the western world, and gene therapy strategies to tackle this disease systemically are often impaired by inefficient delivery of the vector to the tumour tissue. Some of the ...