Browsing by Subject "oncogenic ras"

Now showing items 1-2 of 2

    • Manganese superoxide dismutase induces p53-dependent senescence in colorectal cancer cells 

      Behrend, L.; Mohr, A.; Dick, T.; Zwacka, R. M. (American Society for Microbiology, 2005-08-17)
      The mitochondrial enzyme manganese superoxide dismutase (MnSOD) is known to suppress cell growth in different tumor cell lines. However, the molecular mechanism of this growth-retarding effect is not fully understood. Here ...

    • P53-mediated induction of noxa and p53aip1 requires nfκb 

      O’Prey, Jim; Crighton, Diane; Martin, Angel G.; Vousden, Karen H.; Fearnhead, Howard O.; Ryan, Kevin M. (Informa UK Limited, 2010-03-01)
      The intricate regulation of cell survival and cell death is critical for the existence of both normal and transformed cells. Two factors central to these processes are p53 and NF kappa B, with both factors having ascribed ...