Browsing by Subject "large t-antigen"
Now showing items 1-4 of 4
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Host-specific replication of bk virus dna in mouse cell extracts is independently controlled by dna polymerase -primase and inhibitory activities
(American Society for Microbiology, 2010-04-14)The activation of the human polyomavirus BK causes polyomavirus-associated nephropathy in immuno-compromised humans. Studies of the virus have been restricted since the virus DNA replication is species specific. Cell-based ... -
Initiation of jc virus dna replication in vitro by human and mouse dna polymerase alpha-primase
(Wiley-Blackwell, 2003-05-01)Host species specificity of the polyomaviruses simian virus 40 (SV40) and mouse polyomavirus (PyV) has been shown to be determined by the host DNA polymerase alpha-primase complex involved in the initiation of both viral ... -
Restriction of human polyomavirus bk virus dna replication in murine cells and extracts
(American Society for Microbiology, 2009-03-18)BK virus (BKV) causes persistent and asymptomatic infections in most humans and is the etiologic agent of polyomavirus-associated nephropathy (PVAN) and other pathologies. Unfortunately, there are no animal models with ... -
Stimulation of bk virus dna replication by nfi family transcription factors
(American Society for Microbiology, 2011-12-28)BK polyomavirus (BKV) establishes persistent, low-level, and asymptomatic infections in most humans and causes polyomavirus-associated nephropathy (PVAN) and other pathologies in some individuals. The activation of BKV ...