Browsing by Subject "gtpases"

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    • Rhoa is dispensable for skin development, but crucial for contraction and directed migration of keratinocytes 

      Jackson, B.; Peyrollier, K.; Pedersen, E.; Basse, A.; Karlsson, R.; Wang, Z.; Lefever, T.; Ochsenbein, A. M.; Schmidt, G.; Aktories, K.; Stanley, A.; Quondamatteo, F.; Ladwein, M.; Rottner, K.; van Hengel, J.; Brakebusch, C. (American Society for Cell Biology (ASCB), 2011-01-05)
      RhoA is a small guanosine-5'-triphosphatase (GTPase) suggested to be essential for cytokinesis, stress fiber formation, and epithelial cell-cell contacts. In skin, loss of RhoA was suggested to underlie pemphigus skin ...