Browsing by Subject "generalized born"

Now showing items 1-2 of 2

    • Enzymatic basis forn-glycan sialylation 

      Meng, Lu; Forouhar, Farhad; Thieker, David; Gao, Zhongwei; Ramiah, Annapoorani; Moniz, Heather; Xiang, Yong; Seetharaman, Jayaraman; Milaninia, Sahand; Su, Min; Bridger, Robert; Veillon, Lucas; Azadi, Parastoo; Kornhaber, Gregory; Wells, Lance; Montelione, Gaetano T.; Woods, Robert J.; Tong, Liang; Moremen, Kelley W. (American Society for Biochemistry & Molecular Biology (ASBMB), 2013-10-23)
      Background: Specificity and enzymology of glycan sialylation is poorly understood, despite its importance in biological recognition. Results: ST6GAL1 structure was determined, and substrate binding was modeled to probe ...

    • Predicting the origins of anti-blood group antibody specificity: a case study of the abo a- and b-antigens 

      Makeneni, Spandana; Ji, Ye; Watson, David C.; Young, N. Martin; Woods, Robert J. (Frontiers Media SA, 2014-08-22)
      The ABO blood group system is the most important blood type system in human transfusion medicine. Here, we explore the specificity of antibody recognition toward ABO blood group antigens using computational modeling and ...