Browsing by Subject "gene-transcription"
Now showing items 1-4 of 4
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A localized nucleolar dna damage response facilitates recruitment of the homology-directed repair machinery independent of cell cycle stage
(Cold Spring Harbor Laboratory, 2015-05-27)DNA double-strand breaks (DSBs) are repaired by two main pathways: nonhomologous end-joining and homologous recombination (HR). Repair pathway choice is thought to be determined by cell cycle timing and chromatin context. ... -
Structure-function analysis of hmo1 unveils an ancestral organization of hmg-box factors involved in ribosomal dna transcription from yeast to human
(Oxford University Press (OUP), 2013-09-09)Ribosome biogenesis is a major metabolic effort for growing cells. In Saccharomyces cerevisiae, Hmo1, an abundant high-mobility group box protein (HMGB) binds to the coding region of the RNA polymerase I transcribed ribosomal ... -
Thermotolerance and cell death are distinct cellular responses to stress: dependence on heat shock proteins
(Wiley-Blackwell, 1999-11-15) -
Viral proteins as a potential driver of histone depletion in dinoflagellates
(Springer Nature, 2018-04-18)Within canonical eukaryotic nuclei, DNA is packaged with highly conserved histone proteins into nucleosomes, which facilitate DNA condensation and contribute to genomic regulation. Yet the dinoflagellates, a group of ...