Browsing by Subject "b-DNA"
Now showing items 1-2 of 2
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Methyl-cytosine-driven structural changes enhance adduction kinetics of an exon 7 fragment of the p53 gene
(Springer Nature, 2017-01-19)Methylation of cytosine (C) at C-phosphate-guanine (CpG) sites enhances reactivity of DNA towards electrophiles. Mutations at CpG sites on the p53 tumor suppressor gene that can result from these adductions are in turn ... -
On the molecular basis of uracil recognition in dna: comparative study of t-a versus u-a structure, dynamics and open base pair kinetics
(Oxford University Press (OUP), 2010-09-28)Uracil (U) can be found in DNA as a mismatch paired either to adenine (A) or to guanine (G). Removal of U from DNA is performed by a class of enzymes known as uracil-DNA-glycosylases (UDG). Recent studies suggest that ...