Browsing by Subject "Nucleotide excision repair"
Now showing items 1-2 of 2
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Identification of novel factors that promote trinucleotide repeat instability
(2013-09-23)Trinucleotide repeat (TNR) expansions are the genetic cause of several inherited neurological diseases. Factors that affect the propensity of TNRs to expand include the characteristics of the TNR DNA, the chromatin ... -
Understanding the multifunctional domains of controller protein Centrin2
(NUI Galway, 2018-12-21)Centrin2 is a centrosomal calcium-binding protein that plays a critical role in centriole dynamics and ciliogenesis. Structurally, it has four calcium-binding EF- hand motifs. Most of the cellular centrin2 is not associated ...