Browsing by Subject "Multivariate analysis"
Now showing items 1-4 of 4
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Effects of ball-milling and cryomilling on sulfamerazine polymorphs: A quantitative study
(Elsevier, 2014-04-11)The effects of ball-milling and cryomilling on sulfamerazine forms I and II (SMZ FI, FII) were investigated using X-ray powder diffraction, infrared and near-infrared (NIR) spectroscopy. Cryomilling resulted in a complete ... -
Formation, physical stability, and quantification of process-induced disorder in cryomilled samples of a model polymorphic drug
(Elsevier, 2012-10-09)The formation and physical stability of amorphous sulfathiazole obtained from polymorphic forms I and III by cryomilling was investigated by X-ray powder diffraction (XRPD) and near-infrared (NIR) spectroscopy. Principal ... -
Identifications and quantitative measurements of narcotics in solid mixtures using near-IR Raman spectroscopy and multivariate analysis.
(ASTM International, 1999)Raman spectroscopy offers the potential for the identification of illegal narcotics in seconds by inelastic scattering of light from molecular vibrations. In this study cocaine, heroin, and MDMA were analyzed using near-IR ... -
Quantitative Analysis of the Amorphous Phase and Multiple Polymorphs of Model Sulfa-Drugs; Sulfamerazine and Sulfathiazole
(2013-10-30)Polymorphic transformations are known to occur as a result of many factors, one of the most prominent being recrystallisation from different solutions. Though other factors have been known to induce polymorphic change, ...