Browsing by Author "Prendergast, Lisa"

Now showing items 1-2 of 2

    • Premitotic Assembly of Human CENPs -T and -W Switches Centromeric Chromatin to a Mitotic State. 

      Prendergast, Lisa; van Vuuren, Chelly; Kaczmarczyk, Agnieszka; Quinn, Nadine; Sullivan, Kevin F. (2011)
      Centromeres are differentiated chromatin domains, present once per chromosome, that direct segregation of the genome in mitosis and meiosis by specifying assembly of the kinetochore. They are distinct genetic loci in that ...

    • The cenp-t/-w complex is a binding partner of the histone chaperone fact 

      Prendergast, Lisa; Müller, Sebastian; Liu, Yiwei; Huang, Hongda; Dingli, Florent; Loew, Damarys; Vassias, Isabelle; Patel, Dinshaw J.; Sullivan, Kevin F.; Almouzni, Geneviève (Cold Spring Harbor Laboratory, 2016-06-01)
      The CENP-T/-W histone fold complex, as an integral part of the inner kinetochore, is essential for building a proper kinetochore at the centromere in order to direct chromosome segregation during mitosis. Notably, CENP-T/-W ...