Browsing by Author "O’Reilly, Aoife"

Now showing items 1-2 of 2

    • Stem cells are resistant to trail receptor-mediated apoptosis 

      Szegezdi, Eva; O’Reilly, Aoife; Davy, Yeung; Vawda, Reaz; Taylor, Deanna L.; Murphy, Mary; Samali, Afshin; Mehmet, Huseyin (Wiley-Blackwell, 2009-11-01)
      New therapeutic approaches aim to eradicate tumours by expression of tumouricidal proteins in the tumour stroma. One such anti-neoplastic protein is tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) because ...

    • Targeting aml through dr4 with a novel variant of rhtrail 

      Szegezdi, Eva; Reis, Carlos R.; Sloot, Almer M. van der; Natoni, Alessandro; O’Reilly, Aoife; Reeve, Janice; Cool, Robbert H.; O’Dwyer, Michael; Knapper, Steven; Serrano, Luis; Quax, Wim J.; Samali, Afshin (Wiley-Blackwell, 2011-09-26)
      Despite progress in the treatment of acute myelogenous leukaemia (AML) the outcome often remains poor. Tumour necrosis factor related apoptosis-inducing ligand (TRAIL) is a promising therapeutic agent in many different ...