Browsing by Author "Muttenthaler, Markus"

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    • Subtle modifications to oxytocin produce ligands that retain potency and improved selectivity across species 

      Muttenthaler, Markus; Andersson, Åsa; Vetter, Irina; Menon, Rohit; Busnelli, Marta; Ragnarsson, Lotten; Bergmayr, Christian; Arrowsmith, Sarah; Deuis, Jennifer R.; Chiu, Han Sheng; Palpant, Nathan J.; O’Brien, Margaret; Smith, Terry J.; Wray, Susan; Neumann, Inga D.; Gruber, Christian W.; Lewis, Richard J.; Alewood, Paul F. (American Association for the Advancement of Science (AAAS), 2017-12-05)
      Oxytocin and vasopressin mediate various physiological functions that are important for osmoregulation, reproduction, cardiovascular function, social behavior, memory, and learning through four G protein-coupled receptors ...