Browsing by Title

An investigation of mucus plugging in severe asthma

Dunican, Eleanor (NUI Galway, 2018-05-16)

The classic pathologic finding in patients with fatal asthma is of markedly hyperinflated lungs. This hyperinflation is the consequence of widespread plugging of the segmental and sub-segmental airways. In contrast to fatal ...

Investigation of nanoscale structural alterations of cell nucleus as an early sign of cancer

Alexandrov, Sergey (BioMed Central, 2014)

Background: The cell and tissue structural properties assessed with a conventional bright-field light microscope play a key role in cancer diagnosis, but they sometimes have limited accuracy in detecting early-stage cancers ...

Investigation of nanoscale structural alterations of cell nucleus as an early sign of cancer

Liu, Yang; Uttam, Shikhar; Alexandrov, Sergey; Bista, Rajan K (Springer Nature, 2014-01-01)

Background: The cell and tissue structural properties assessed with a conventional bright-field light microscope play a key role in cancer diagnosis, but they sometimes have limited accuracy in detecting early-stage cancers ...

An investigation of neuroanatomical contributions to cognitive deficits associated with psychotic illness: A 4 year longitudinal follow-up study

Kenney, Joanne (2017-02-20)

Introduction: In general, individuals who experience a first-episode of psychosis (FEP) display deficits on a wide range of neuropsychological tasks compared to psychiatrically healthy individuals (Bora et al., 2014). ...

Investigation of non-covalent interactions of metal complexes with DNA in cell-free systems

Erxleben, Andrea (Schweizerische Chemische Gesellschaft, 2017-03-01)

Non-covalent interactions of metallo compounds with DNA range from the simple, unspecific electrostatic binding of a positively charged metal complex to the sequence-selective recognition of DNA binding sites due to shape, ...

An Investigation of Nurse's Work-Life Balance in Public Sector Hospitals in Ireland

Browne, Patricia (2012)

"Nurses are the single largest group of registered and regulated practitioners in the health workforce of any country and are internationally recognised as being fundamental to the provision of health care" (WHO:2002). The ...

Investigation of pathogenic vibrio in Irish aquaculture

Boyle, Katie Louise (NUI Galway, 2023-07-31)

Vibrio parahaemolyticus, Vibrio vulnificus and Vibrio cholerae are marine pathogens that cause gastroenteritis in humans after the consumption of infected shellfish. Vibrio can cause devastating losses of oysters, shrimps ...

Investigation of prolific sheep from uk and ireland for evidence on origin of the mutations in bmp15 (fecxg, fecxb) and gdf9 (fecgh) in belclare and cambridge sheep

Mullen, Michael P.; Hanrahan, James P.; Howard, Dawn J.; Powell, Richard (Public Library of Science (PLoS), 2013-01-02)

This paper concerns the likely origin of three mutations with large effects on ovulation rate identified in the Belclare and Cambridge sheep breeds; two in the BMP15 gene (FecX(G) and FecX(B)) and the third (FecG(H)) in ...

Investigation of radon prevention and mitigation: from radon measurements to specification for soil depressurisation systems

Fuente Lastra, Marta (NUI Galway, 2020-01-27)

Reduction of indoor radon concentration in buildings is considered to be an important public health issue, since radon was recognised as the leading cause of lung cancer after tobacco smoking by the World Health Organisation. ...

An investigation of reading abilities and the impact of programmed instruction on reading outcomes in children with autism specrtum disorder

Nally, Amanda (NUI Galway, 2018-05-11)

This thesis investigates reading abilities and programmed instruction, i.e., instruction that is scripted and sequenced, with explicit learning goals, based on the principles of Applied Behaviour Analysis, in children with ...

Investigation of sexual dimorphism in an animal model of neuropathic pain: role of the endocannabinoid system

Boullon, Laura (NUI Galway, 2023-05-15)

Although the presence of sexual dimorphism in the symptomatology of neuropathic pain is well-established, the neurobiology underlying sex differences in pain processing and modulation remains unclear. Gonadal hormones ...

Investigation of T cell receptor and immunoglobulin repertoire through next generation sequencing data

Yu, Yaxuan (2017-08-08)

The diversity of the immunological repertoire has long been a subject of research focus, providing important insights into the adaptive immune system. Rapid developments in next generation sequencing technologies ...

An investigation of the age and severity of autism spectrum disorder diagnosis in children and adolescents with and without a co-occurring diagnosis

Hogan, Amy; Leader, Geraldine; Mannion, Arlene (The Psychological Society of Ireland, 2017-04)

The aim of this study is to investigate the age of diagnosis of children with a diagnosis of Autism Spectrum Disorder (ASD) in comparison to children with a diagnosis of ASD and comorbid disorders. It will also look at ...

Investigation of the application of process analytical technology for a laser welding process in medical device manufacturing

Moore, Sean; Conneely, Alan; Stenzel, Eric; Murphy, Eamonn (Elsevier BV, 2011-01-01)

In FDA regulated medical device manufacturing, real time inspection of manufactured product is limited by the requirement to destructively test random samples of the product post production. Infra Red thermography offers ...

Investigation of the capacity of low glass transition temperature excipients to minimize amorphization of sulfadimidine on comilling

Curtin, Vincent; Amharar, Youness; Hu, Yun; Erxleben, Andrea; McArdle, Patrick; Caron, Vincent; Tajber, Lidia; Corrigan, Owen I.; Healy, Anne Marie (American Chemical Society (ACS), 2013-01-07)

The coprocessing of active pharmaceutical ingredient (API) with an excipient which has a high glass transition temperature (T-g) is a recognized strategy to stabilize the amorphous form of a drug. This work investigates ...