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Now showing items 6581-6600 of 14643
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Immunocompromised patients with acute respiratory distress syndrome: secondary analysis of the lung safe database
(Springer Nature, 2018-06-12)Background: The aim of this study was to describe data on epidemiology, ventilatory management, and outcome of acute respiratory distress syndrome (ARDS) in immunocompromised patients. Methods: We performed a post hoc ... -
Immunogenicity of allogeneic mesenchymal stem cells
(2012)Mesenchymal stem cells (MSCs) inhibit proliferation of allogeneic T cells and express low levels of major histocompatibility complex class I (MHCI), MHCII and vascular adhesion molecule-1 (VCAM-1). We investigated whether ... -
Immunogenicity of allogeneic mesenchymal stem cells
(Wiley-Blackwell, 2012-08-23)Mesenchymal stem cells (MSCs) inhibit proliferation of allogeneic T cells and express low levels of major histocompatibility complex class I (MHCI), MHCII and vascular adhesion molecule-1 (VCAM-1). We investigated whether ... -
Immunogenicity of allogeneic mesenchymal stem cells
(2016-10-20)Allogeneic mesenchymal stem cells (allo-MSC) are a promising “off-the-shelf” therapy and are often cited as failing to elicit anti-donor immune responses. Intra-muscular (IM) administration may be the optimal route for ... -
Immunogenomics of gastrointestinal nematode infection in ruminants - breeding for resistance to produce food sustainably and safely
(Wiley-Blackwell, 2016-09-01)Gastrointestinal nematode (GIN) infection of ruminants represents a major health and welfare challenge for livestock producers worldwide. The emergence of anthelmintic resistance in important GIN species and the associated ... -
Immunological aspects of allogeneic mesenchymal stem cell therapies
(Mary Ann Liebert Inc, 2010-12-01)Allogeneic mesenchymal stem or stromal cells (MSCs) are proposed as cell therapies for degenerative, inflammatory, and autoimmune diseases. The feasibility of allogeneic MSC therapies rests heavily on the concept that these ... -
Immunological comparison of human pyruvate kinase isoenzymes
(Portland Press Ltd., 1977-10-01) -
Immunological research in clinical psychiatry: report on the consensus debate during the 7th expert meeting on psychiatry and immunology
(Springer Nature, 2002-01-01)There is convincing evidence that cytokines are involved in the physiology and pathophysiology of brain function and interact with different neurotransmitter and neuroendocrine pathways. The possible involvement of the ... -
Immunomodulation by interleukin-10 overexpressing mesenchymal stem cells for cartilage repair in osteoarthritis
(2015-03-06)Although osteoarthritis (OA) is typically characterised by the loss or damage to articular cartilage, inflammation of the synovial membrane is now recognised as a prevalent feature believed to contribute to both symptoms ... -
Immunomodulation in mesenchymal stem cell therapy for osteoarthritis: mechanistic insights on the role of cell death and engraftment
(NUI Galway, 2018-11-02)Osteoarthritis (OA) is a degenerative pathology of the articular cartilage causing chronic pain and disability in millions of individuals. In OA synovia, resident macrophages and infiltrated lymphocytes contribute to the ... -
Immunomodulation of the T-helper 17 Cell Lineage by Mesenchymal Stem Cells
(2012-11-20)T-helper 17 (Th17) cells play a pathogenic role in multiple sclerosis, inflammatory bowel disease, psoriasis, acute kidney injury, glomerulonephritis and transplant rejection. Mesenchymal stem cells (MSCs) are immunosuppressive ... -
Immunomodulatory function of licensed human bone marrow mesenchymal stromal cell-derived apoptotic bodies
(Elsevier, 2023-10-23)Background Mesenchymal stromal cells (MSCs) show great potential for immunomodulatory and anti-inflammatory treatments. Clinical trials have been performed for the treatment of Type 1 diabetes, graft-versus-host disease ... -
Impact evaluation of an HIV screen educational advertisement
(Emerald, 2000-02)An advertisement explicitly depicting behaviours associated with transmission of HIV was developed with the aim of reminding people of the continued threat posed by the virus to health. Evaluation of the advertisement was ... -
Impact evaluation of an oral health intervention amongst primary school children in ireland
(Oxford University Press (OUP), 2002-06-01)A pilot oral health programme was developed which aimed to improve dental health knowledge and behaviour amongst Irish school children aged 7-12 years. The programme comprised two integral components: a television campaign, ... -
Impact evaluation of an oral health intervention amongst primary school children in Ireland.
(Oxford Journals, 2002-06)A pilot oral health programme was developed which aimed to improve dental health knowledge and behaviour amongst Irish school children aged 7-12 years. The programme comprised two integral components: a television campaign, ... -
Impact of a national external quality assessment scheme for breast pathology in the uk
(BMJ, 2006-02-01)Background: This article presents the results and observed effects of the UK National Health Service Breast Screening Programme (NHSBSP) external quality assurance scheme in breast histopathology. Aims/Methods: The major ... -
Impact of adverse events, treatment modifications, and dose intensity on survival among patients with advanced renal cell carcinoma treated with first-line sunitinib: a medical chart review across ten centers in five european countries
(Wiley-Blackwell, 2014-07-18)Angiogenesis inhibitors have become standard of care for advanced and/or metastatic renal cell carcinoma (RCC), but data on the impact of adverse events (AEs) and treatment modifications associated with these agents are ... -
The Impact of Agile Practices on Trust in Software Project Teams
(IEEE, 2012)Agile software development involves self-managing teams that are empowered and responsible for meeting project goals in whatever way they deem suitable. Managers must place more trust in such teams than they do in teams ... -
The impact of alcohol consumption on brain networks: Investigating differential effects in bipolar disorder
(NUI Galway, 2022-03-30)Background: Widespread alterations to cortical regions particularly in areas related to reward processes have been described following non-dependent alcohol use and independently in bipolar disorder (BD). Additionally, ...