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Now showing items 3233-3252 of 14593
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Design, development and validation of a series of multiplex real-time PCR diagnostics assays for the rapid and accurate detection and differentiation of the Mycobacterium tuberculosis complex
(2012-03-01)Tuberculosis (TB) remains a major health concern both in developed and developing countries due to the high rates of morbidity and mortality associated with disease. In humans, TB is caused by members of the Mycobacterium ... -
The Design, Development and Validation of a Wearable Behaviour Monitor for the Autonomous Assessment of the Functional Health of Older Adults
(2013-12-23)Functional ability describes a person's capability to perform those tasks that are necessary to live independently. It is a proven predictor of functional decline, the need for hospitalisation and institutionalisation ... -
The design, manufacture and testing of a composite polysialic acid mimetic peptide loaded collagen nerve graft for use in peripheral nerve repair
(NUI Galway, 2016-02-15)Peripheral nerve injuries can be debilitating for patients. The current gold-standard technique for peripheral nerve repair is autograft. This procedure involves harvesting a non-critical nerve from a donor site from the ... -
Design, synthesis and catalytic activity of novel oxazoline based ligands
(2015-08-14)This thesis can be viewed as two separate studies. Firstly, the design, synthesis and catalytic activity of novel 2-pyridyl mono(oxazoline). A family of mono(oxazoline) ligands were developed in which the 5-poition is ... -
Design, synthesis and evaluation of glycomimetics as galectin inhibitors
(NUI Galway, 2024-03-11)Chapter-1: This chapter begins with a short review on carbohydrates and their structure and then summarises some highlights from the last two decades of research on developing carbohydrate-based drug candidates. Included ... -
Design, synthesis, and public understanding and involvement in randomised trials
(NUI Galway, 2021-03-16)Introduction The initial aim of my PhD was to assess if amniotic membrane sweeping, a common intervention in maternity care, is a safe and effective way of preventing a formal induction of labour1 in pregnant women at ... -
DESIGN-ED: a pedagogical toolkit to support K-12 teachers’ emergency transition to remote online education
(Emerald, 2020-06-23)K-12 educators face persistent and nascent challenges as they grapple with making an emergency transition to remote online modes of engaging with their students. Crossing the digital divide that exists between multi-site ... -
Designed tumor necrosis factor-related apoptosis-inducing ligand variants initiating apoptosis exclusively via the dr5 receptor
(Proceedings of the National Academy of Sciences, 2006-05-26)Tumor necrosis factor-related apoptosis-inclucing ligand (TRAIL) is a potential anticancer drug that selectively induces apoptosis in a variety of cancer cells by interacting with death receptors DR4 and DR5. TRAIL can ... -
Designing an acceptable and useful companion robot for people with dementia and carers in Ireland: the MARIO project
(NUI Galway, 2016-10-31)[No abstract available] -
Designing blended learning for accounting in tertiary education: The PACE-IT model
(NUI Galway, 2020-10-29)Technological advancements have engendered evolving work roles for professional accountants as they navigate the trajectory of their careers. This has prompted calls for the transformation of accounting education at ... -
Designing digital storytelling: creative technology for reflection in initial teacher education
(2014-03-03)Reflection represents a foundational, core developmental activity in teacher professional education. Reflection can, however, prove challenging, and even problematic, particularly for novice, pre-service teachers (Calderhead, ... -
Designing environmentally efficient aquafeeds through the use of multicriteria decision support tools
(Elsevier, 2021-05-21)Aquaculture is the fastest growing food production system, and the sector accounts for more than half of all fish consumed. Its potential as a sustainable food source has been recognised within the EU Farm to Fork strategy ... -
Designing for emergency remote blended and online education: a response to Bennett et al. (2017)
(Springer, 2020-11-20)This paper is in response to the article entitled The process of designing for learning: understanding university teachers design work (Bennett et al. in Educ Technol Res Dev 65(1):125 145, 2017). Design constitutes a ... -
Designing futures through student engagement: A policy futures perspective
(SAGE Publications, 2023-06-12)Futures research is gaining increased prominence in educational research and development (Tesar, 2021), and particularly now as we emerge from the global COVID-19 pandemic, which has provided a lever for change and an ... -
Designing online delivery of lean education during COVID-19
(Emerald, 2023-08-23)This study describes how two organisations transitioned to teaching Lean online during and post Covid-19. The study aims to establish how Lean teaching and training can be designed and delivered effectively online without ... -
Designing physics video hooks for science students
(IOP Publishing, 2015-12-17)This paper offers an insight into the design structure of physics video hooks that were developed by the Science Education Resource design team in the school of education (SOE) in National University of Ireland, Galway ... -
Designing real-world laboratories for the reduction of residential energy use: Articulating theories of change
(Oekom Verlag, 2018-01-01)Reducing residential energy use and carbon dioxide emissions is a policy concern across Europe. One of the approaches to address this problem, real-world laboratories (RwLs), has recently gained prominence as a means to ... -
Designing real-world laboratories for the reduction of residential energy use: articulating theories of change
(Oekom Publishers GmbH, 2018-01-01)Reducing residential energy use and carbon dioxide emissions is a policy concern across Europe. One of the approaches to address this problem, real-world laboratories (RwLs), has recently gained prominence as a means to ... -
Desman: a new tool for de novo extraction of strains from metagenomes
(Springer Nature, 2017-09-21)We introduce DESMAN for De novo Extraction of Strains from Metagenomes. Large multi-sample metagenomes are being generated but strain variation results in fragmentary co-assemblies. Current algorithms can bin contigs into ... -
Desmosomal armadillo proteins in zebrafish cardiac development
(2012-12-18)Plakoglobin and plakophilin-2 are desmosomal armadillo proteins, required for correct cardiac development in zebrafish. Mutations in the human genes can cause the congenital heart defect arrhythmogenic right ventricular ...