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Now showing items 8336-8355 of 14643
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Mechanisms of flooding in Cork City
(International Association of Hydrological Sciences, 2015-11-17)Flooding is one of the most frequent and devastating natural disasters. Many urban developments are located in estuaries where river flow and sea water merge. Cork City situated in the River Lee estuary frequently subject ... -
Mechanisms of iron sulfide-based autotrophic denitrification for removal of nutrients and emerging contaminants from carbon-deficient wastewater
(NUI Galway, 2023-09-19)Autotrophic denitrification is a biological nitrogen removal process in which nitrate (NO3 - ) is reduced to nitrogen gas (N2) by chemoautotrophic denitrifying bacteria in the presence of inorganic electron donors ... -
Mechanisms of osteocyte stimulation in osteoporosis
(Elsevier, 2016-05-10)Experimental studies have shown that primary osteoporosis' caused by oestrogen deficiency results in localised alterations in bone tissue properties and mineral composition. Additionally, changes to the lacunar-canalicular ... -
Mechanisms of osteocyte stimulation in osteoporosis
(Elsevier BV, 2016-09-01) -
Mechanistic and kinetic study on the anomerisation reaction and application in pharmaceutical research
(NUI Galway, 2024-01-08)It is becoming increasingly apparent that carbohydrate-based pharmaceutically active compounds (PACs) play a key role in pharmaceutical advancement. Many new carbohydrate-based PACs have recently been developed with a ... -
Mechanistic insights into novel cellular therapy strategies for the treatment of corneal allograft rejection
(NUI Galway, 2019-02-14)It has previously been demonstrated by our lab that tolerogenic dendritic cells (tDCs) prolong corneal allograft survival. This study revealed that tDCs had significantly higher levels of sialic acid on the cell surface ... -
The mechano-sorptive creep behaviour of basalt FRP reinforced timber elements in a variable climate
(Elsevier, 2019-09-25)The use of Fibre Reinforced Polymer (FRP) reinforcement has been shown to improve the short-term flexural behaviour of timber elements. This is particularly important when reinforced elements are subjected to a variable ... -
Mechano-sorptive creep in reinforced glulam
(National University of Ireland Galway, 2018-08-20)An investigation was carried out to examine the effect of reinforcement on the creep behaviour of FRP reinforced timber elements in a controlled variable climate. Creep is accelerated by moisture variations due to a ... -
Mechanobiological changes during estrogen deficiency leading to bone loss
(NUI Galway, 2019-12-18)Osteoporosis, which predominantly occurs in females, affects 200 million women worldwide and is characterised by bone loss and microarchitectural degradation, which leads to fractures, pain and immobility. Conventional ... -
Mechanobiological origins of osteolysis during bone metastasis
(NUI Galway, 2023-03-28)Metastasis is the final, lethal stage of cancer where cells migrate from a primary tumour site to colonise a secondary organ and is the primary cause of mortality in cancer patients. Breast cancer is the leading cause ... -
Mechanobiological Origins of Osteoporosis
(2013-09-30)The osteocyte is believed to act as the primary sensor of mechanical stimulus in bone, controlling signalling for bone growth and resorption in response to changes in the mechanical demands placed on bones throughout life. ... -
Mechanochemical tuning of the binaphthyl conformation at the air water interface
(Wiley, 2015-06-12)Gradual and reversible tuning of the torsion angle of an amphiphilic chiral binaphthyl, from −90° to −80°, was achieved by application of a mechanical force to its molecular monolayer at the air–water interface. This 2D ... -
Media accountability in the twenty-first century
(2012-10-02)This thesis provides a comprehensive examination, analysis and assessment of the strengths and weaknesses of the various methods currently used to ensure media accountability in Ireland and in other jurisdictions. It ... -
Media and disability - issues of portrayal and access
(2016-04-29)This thesis begins with the premise that freedom of expression is the cornerstone of a democracy and any limitation on it must be prescribed by law, be in support of a legitimate aim and be necessary in a democratic society. ... -
Media matters: Impact of expansion media on the phenotype of mesenchymal stromal cells
(NUI Galway, 2023-03-02)Despite a long history of investigation and sustained efforts in clinical testing with large numbers of clinical trials being initiated, the number of market authorisations for mesenchymal stromal cell (MSC) therapies ... -
Mediated electron transfer of cellobiose dehydrogenase and glucose oxidase at osmium polymer-modified nanoporous gold electrodes
(Springer Nature, 2012-12-30)Nanoporous and planar gold electrodes were utilised as supports for the redox enzymes Aspergillus niger glucose oxidase (GOx) and Corynascus thermophilus cellobiose dehydrogenase (CtCDH). Electrodes modified with hydrogels ... -
Mediated glucose biosensors for application in continuous glucose monitoring
(NUI Galway, 2023-04-19)Diabetes affects 1 in 11 people globally and requires monitoring of blood glucose levels as a part of its treatment. Initial blood glucose monitoring devices involved finger prick testing at regular intervals daily, a ... -
Mediating alternative imaginaries of aid and development: The possibilities and challenges for contemporary NGOs
(NUI Galway, 2020-03-14)This thesis extends considerations around the role that geography can play in disrupting dominant representational tropes through which Global North publics understand distant people and places. Through a focus on NGO ... -
Mediators of endoplasmic reticulum stress-induced apoptosis
(Wiley-Blackwell, 2006-09-01)The efficient functioning of the endoplasmic reticulum ( ER) is essential for most cellular activities and survival. Conditions that interfere with ER function lead to the accumulation and aggregation of unfolded proteins. ... -
Medical devices for the minimally invasive delivery of therapeutic cargo for the prevention of heart failure
(NUI Galway, 2020-11-10)Therapeutic advances are increasing the number of patients that survive cardiac disease such as a myocardial infarction, however, current treatments do not fully stop the development of heart failure. Advanced therapeutic ...