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Now showing items 11119-11138 of 14641
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Regulation of eukaryotic dna replication at the initiation step
(Portland Press Ltd., 2003-02-01)The studies of cell growth and division have remained at the centre of biomedical research for more than 100 years. The combination of genetic, biochemical, molecular and cell biological techniques recently yielded a burst ... -
Regulation of fear, anxiety and cognition in the presence or absence of pain by peroxisome proliferator-activated receptors
(NUI Galway, 2019-06-07)Fear/anxiety and pain modulate one another reciprocally, but the neurobiological mechanisms that underlie this interaction are not completely understood. Fear-conditioned analgesia (FCA) is pain suppression upon exposure ... -
Regulation Of Myometrial Gene Expression By Oestrogen And Progesterone: The Use Of A Cell Culture Model To Mimic The In Vivo Conditions Of Pregnant Human Uterus
(2012-12-31)Pregnancy and labour are physiological events controlled by a complex interplay between maternal and foetal factors. These processes are diverse and specific to each species, hence simple extrapolation from model organisms ... -
Regulation of nf- b responses by epigenetic suppression of i b expression in hct116 intestinal epithelial cells
(American Physiological Society, 2010-04-08)O'Gorman A, Colleran A, Ryan A, Mann J, Egan LJ. Regulation of NF-kappa B responses by epigenetic suppression of I kappa B alpha expression in HCT116 intestinal epithelial cells. Am J Physiol Gastrointest Liver Physiol ... -
Regulation of Six1 and Eya1 during the formation of the preplacodal ectoderm in xenopus - towards a gene regulatory network of the developing neural plate border
(2017-01-06)Cranial placodes are ectodermal thickenings in vertebrate embryos that give rise to many sense organs and ganglia. All placodes arise from a common precursor, the pre-placodal ectoderm (PPE). The latter develops during ... -
The regulation of starch synthesis by phytochrome A&B, thioredoxins and plastidial kinases in Arabidopsis thaliana leaves
(2017-08-09)Starch is an important storage carbon in many plant leaves which is synthesized during the day and degraded at night to maintain cellular maintenance and eventually growth. The biosynthesis of starch is a highly regulated ... -
The Regulation of Stem Cell Research in Ireland
(2013-03-19)This thesis explores the regulation of stem cell research internationally with a view to providing a suitable regulatory framework for Ireland. It examines the ethical, legal and economic issues which can is raised by stem ... -
Regulation of surfactant protein b gene expression in bone marrow-derived cells
(Wiley-Blackwell, 2009-03-01)While investigating the differentiation potential of bone marrow-derived cells, we previously demonstrated upregulated expression of the lung-related surfactant protein B (SP-B) gene in hematopoietic progenitor cells (HPCs) ... -
Regulation of the DNA Damage Response and Gene Expression by the Dot1L Histone Methyltransferase and the 53Bp1 Tumour Suppressor
(PLoS, 2011-02)Background Dot1L, a histone methyltransferase that targets histone H3 lysine 79 (H3K79), has been implicated in gene regulation and the DNA damage response although its functions in these processes remain poorly ... -
Regulation of the dna damage response and gene expression by the dot1l histone methyltransferase and the 53bp1 tumour suppressor
(Public Library of Science (PLoS), 2011-02-24)Background: Dot1L, a histone methyltransferase that targets histone H3 lysine 79 (H3K79), has been implicated in gene regulation and the DNA damage response although its functions in these processes remain poorly ... -
The Regulation of the Legal Profession in Ireland
(2013-09-30)This thesis seeks to explore the regulation of the legal profession in Ireland and to identify whether changes ought to be made to the present regulatory regime. Against a background of economic collapse and Troika bailout, ... -
Regulation of the unfolded protein response by noncoding rna
(American Physiological Society, 2017-09-01)Cells are exposed to various intrinsic and extrinsic stresses in both physiological and pathological conditions. To adapt to those conditions, cells have evolved various mechanisms to cope with the disturbances in protein ... -
Regulators of TRAIL resistance in normal and transformed cells
(2015-05-26)TRAIL is a member of the Tumor Necrosis Factor superfamily which was shown to be able to induce apoptotic cell death in a wide variety of transformed cells, leaving normal, healthy cells unharmed. However, approximately ... -
Regulatory regions and critical residues of nod2 involved in muramyl dipeptide recognition
(Wiley-Blackwell, 2004-03-25)Multiple genetic variants of CARD15/NOD2 have been associated with susceptibility to Crohn's disease and Blau syndrome. NOD2 recognizes muramyl dipeptide (MDP) derived from bacterial peptidoglycan (PGN), but the molecular ... -
Rehabilitation approaches in dementia: an evaluation of three interventions from an occupational therapy perspective
(2017-01-25)Dementia is a complex, progressively degenerative condition resulting in loss of cognitive and functional capabilities, along with a significant increase in degree of dependency. In recent years a number of non-pharmacological ... -
Reimagining a framework for teachers’ continuous professional development during curriculum reform
(Taylor and Francis Group, 2023-09-04)Effective continued professional development (CPD) is critical in preparing teachers for implementing curricular changes. Utilising the professional design framework [Loucks-Horsley, S., Stiles, K. E., Mundry, S. E., Love, ... -
Reimagining adoption in Ireland: a viable option for children in care?
(Taylor & Francis, 2017-07-03)This article considers how adoption may develop as viable option for permanency planning for children in care in Ireland following the Constitutional Referendum in 2012 on Children s Rights. In order to be prepared to ... -
Reimagining an Irish City: I am Belfast
(Asociación Española de Estudios Irlandeses, Spanish Association for Irish Studies (AEDEI), 2017-03)An early shot in Mark Cousin's I am Belfast lingers on a very unusual and unexpected landscape, what appears to be an icy vista reflected in water, with clouds drifting by in the distance. Where s this our narrator asks. ... -
Reimagining Research and Education in Higher Education - integrating scholarships for sustainable human development
(Commonwealth Secretariat / Nexus Strategic Partnerships, 2014-11-27)This contribution examines key intersections between development, higher education and research. It suggests that the interactions between these domains are neglected and argues that higher education s contribution needs ... -
Reimagining the Fourth Age: The ageing mother in the poetry of Mary Dorcey and Paul Durcan
(Nordic Irish Studies Network, 2018)In my analysis of selected poems by Mary Dorcey and Paul Durcan, literary representations of the ageing mother are explored in conjunction with research in cultural and social gerontology relating to the demographic group ...