Browsing University of Galway Support Services by Author "Newell, John"
Now showing items 21-35 of 35
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Relationship between circulating and tissue micrornas in a murine model of breast cancer
Waters, Peadar S.; McDermott, Ailbhe M.; Wall, Deirdre; Heneghan, Helen M.; Miller, Nicola; Newell, John; Kerin, Michael J.; Dwyer, Róisín M. (Public Library of Science (PLoS), 2012-11-30)MiRNAs are key regulators of tumorigenesis that are aberrantly expressed in the circulation and tissue of patients with cancer. The aim of this study was to determine whether miRNA dysregulation in the circulation reflected ... -
Screening uptake rates and the clinical and cost effectiveness of screening for gestational diabetes mellitus in primary versus secondary care: study protocol for a randomised controlled trial
O’Dea, Angela; Infanti, Jennifer J; Gillespie, Paddy; Tummon, Olga; Fanous, Samuel; Glynn, Liam G; McGuire, Brian E; Newell, John; Dunne, Fidelma P (Springer Nature, 2014-01-01)Background: The risks associated with gestational diabetes mellitus (GDM) are well recognized, and there is increasing evidence to support treatment of the condition. However, clear guidance on the ideal approach to screening ... -
Sexual counselling for patients with cardiovascular disease: protocol for a pilot study of the charms sexual counselling intervention
Murphy, Patrick J; Mc Sharry, Jenny; Casey, Dympna; Doherty, Sally; Gillespie, Paddy; Jaarsma, Tiny; Murphy, Andrew W; Newell, John; O'Donnell, Martin; Steinke, Elaine E; Toomey, Elaine; Byrne, Molly (BMJ, 2016-06-01)Introduction Sexual problems are common with cardiovascular disease, and can negatively impact quality of life. To address sexual problems, guidelines have identified the importance of sexual counselling during cardiac ... -
Sleep to lower elevated blood pressure: a randomized controlled trial (slept)
McGrath, Emer R.; Espie, Colin A.; Power, Alice; Murphy, Andrew W.; Newell, John; Kelly, Caroline; Duffy, Niamh; Gunning, Patricia; Gibson, Irene; Bostock, Sophie; O’Donnell, Martin J. (Oxford University Press (OUP), 2017-01-19)BACKGROUND Impaired sleep quality is common and associated with an increased risk of cardiovascular disease (CVD), thought to be mediated through adverse effects on established vascular risk factors, particularly hypertension. ... -
Sleep to lower elevated blood pressure: study protocol for a randomized controlled trial
McGrath, Emer R; Espie, Colin A; Murphy, Andrew W; Newell, John; Power, Alice; Madden, Sarah; Byrne, Molly; O’Donnell, Martin J (Springer Nature, 2014-10-09)Background: Sleep is an essential component of good physical and mental health. Previous studies have reported that poor quality sleep is associated with an increased risk of hypertension and cardiovascular disease. ... -
Smart move - a smartphone-based intervention to promote physical activity in primary care: study protocol for a randomized controlled trial
Glynn, Liam G; Hayes, Patrick S; Casey, Monica; Glynn, Fergus; Alvarez-Iglesias, Alberto; Newell, John; ÓLaighin, Gearóid; Heaney, David; Murphy, Andrew W (Springer Nature, 2013-01-01)Background: Sedentary lifestyles are now becoming a major concern for governments of developed and developing countries with physical inactivity related to increased all-cause mortality, lower quality of life, and increased ... -
Summarising censored survival data using the mean residual life function
Alvarez-Iglesias, Alberto; Newell, John; Scarrott, Carl; Hinde, John (Wiley-Blackwell, 2015-01-28) -
The cost-effectiveness of a structured education pulmonary rehabilitation programme for chronic obstructive pulmonary disease in primary care: the prince cluster randomised trial
Gillespie, Paddy; O'Shea, Eamon; Casey, Dympna; Murphy, Kathy; Devane, Declan; Cooney, Adeline; Mee, Lorraine; Kirwan, Collette; McCarthy, Bernard; Newell, John; , (BMJ, 2013-11-01)Objective To assess the cost-effectiveness of a structured education pulmonary rehabilitation programme (SEPRP) for chronic obstructive pulmonary disease (COPD) relative to usual practice in primary care. The programme ... -
The effectiveness of a structured education pulmonary rehabilitation programme for improving the health status of people with moderate and severe chronic obstructive pulmonary disease in primary care: the prince cluster randomised trial
Casey, Dympna; Murphy, Kathy; Devane, Declan; Cooney, Adeline; McCarthy, Bernard; Mee, Lorraine; Newell, John; O'Shea, Eamon; Scarrott, Carl; Gillespie, Paddy; Kirwan, Collette; Murphy, Andrew W (BMJ, 2013-06-04)Objective To evaluate the effectiveness of a structured education pulmonary rehabilitation programme on the health status of people with chronic obstructive pulmonary disease (COPD). Design Two-arm, cluster randomised ... -
The fairness, predictive validity and acceptability of multiple mini interview in an internationally diverse student population- a mixed methods study
Kelly, Maureen E; Dowell, Jon; Husbands, Adrian; Newell, John; O‘Flynn, Siun; Kropmans, Thomas; Dunne, Fidelma P; Murphy, Andrew W (Springer Nature, 2014-12-01)Background: International medical students, those attending medical school outside of their country of citizenship, account for a growing proportion of medical undergraduates worldwide. This study aimed to establish the ... -
The impact of renal insufficiency and anaemia on survival in patients with cardiovascular disease: a cohort study
Anderson, Jocelyn; Glynn, Liam G; Newell, John; Iglesias, Alberto A; Reddan, Donal; Murphy, Andrew W (Springer Nature, 2009-11-12)Background: The simultaneous occurrence of cardiovascular disease (CVD), kidney disease, and anaemia is associated with increased morbidity and mortality. In the community setting, little data exists about the risk associated ... -
The irish dafne study protocol: a cluster randomised trial of group versus individual follow-up after structured education for type 1 diabetes
Dinneen, Seán F; ,; O' Hara, Mary Clare; Byrne, Molly; Newell, John; Daly, Lisa; O' Shea, Donal; Smith, Diarmuid (Springer Nature, 2009-09-23)Background: Structured education programmes for individuals with Type 1 diabetes have become a recognised means of delivering the knowledge and skills necessary for optimal self-management of the condition. The Dose ... -
The sodium iodide symporter (nis) and potential regulators in normal, benign and malignant human breast tissue
Ryan, James; Curran, Catherine E.; Hennessy, Emer; Newell, John; Morris, John C.; Kerin, Michael J.; Dwyer, Róisín M. (Public Library of Science (PLoS), 2011-01-19)Introduction: The presence, relevance and regulation of the Sodium Iodide Symporter (NIS) in human mammary tissue remains poorly understood. This study aimed to quantify relative expression of NIS and putative regulators ... -
To what extent does the health professions admission test-ireland predict performance in early undergraduate tests of communication and clinical skills? – an observational cohort study
Kelly, Maureen E; Regan, Daniel; Dunne, Fidelma; Henn, Patrick; Newell, John; O’Flynn, Siun (Springer Nature, 2013-05-10)Background: Internationally, tests of general mental ability are used in the selection of medical students. Examples include the Medical College Admission Test, Undergraduate Medicine and Health Sciences Admission Test and ... -
Who eats four or more servings of fruit and vegetables per day? multivariate classification tree analysis of data from the 1998 survey of lifestyle, attitudes and nutrition in the republic of ireland
Friel, Sharon; Newell, John; Kelleher, Cecily (Cambridge University Press (CUP), 2005-04-01)Objective: To identify, using the novel application of multivariate classification trees, the socio-economic, sociodemographic and health-related lifestyle behaviour profile of adults who comply with the recommended 4 or ...