Browsing National Centre for Biomedical Engineering Science (Scholarly Articles) by Author "Golden, Aaron"
Now showing items 1-3 of 3
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Alignment-free clustering of transcription factor binding motifs using a genetic-k-medoids approach
Ó Broin, Pilib; Smith, Terry J.; Golden, Aaron (BioMed Central, 2015-01-28)Background: Familial binding profiles (FBPs) represent the average binding specificity for a group of structurally related DNA-binding proteins. The construction of such profiles allows the classification of novel motifs ... -
Gene prediction using the Self-Organizing Map: automatic generation of multiple gene models
McInerney, James O; Smith, Terry; Mahony, Shaun; Golden, Aaron (BioMed Central, 2005-03-05)Background: Many current gene prediction methods use only one model to represent protein-coding regions in a genome, and so are less likely to predict the location of genes that have an atypical sequence composition. It ... -
Transcription factor binding site identification using the Self-Organizing Map
Mahony, Shaun; Hendrix, David; Golden, Aaron; Smith, Terry (Oxford Open Journals, 2005-05-01)Motivation: The automatic identification of over-represented motifs present in a collection of sequences continues to be a challenging problem in computational biology. In this paper, we propose a self-organizing map of ...