Browsing Pharmacology & Therapeutics by Author "Science Foundation Ireland"
Now showing items 1-2 of 2
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Inhibition by Anandamide of 6-Hydroxydopamine-Induced Cell Death in PC12 Cells
Mnich, Katarzyna; Finn, David P.; Dowd, Eilis; Gorman, Adrienne M. (2010)6-hydroxydopamine (6-OHDA) is a selective neurotoxin that is widely used to investigate cell death and protective strategies in models of Parkinson's disease. Here, we investigated the effects of the endogenous cannabinoid, ... -
Pharmacological inhibition of endocannabinoid degradation modulates the expression of inflammatory mediators in the hypothalamus following an immunological stressor
Kerr, D.M.; Burke, N.N.; Ford, Gemma K.; Harhen, Brendan; Egan, Laurence J.; Finn, David P.; Roche, Michelle (Elsevier, 2011-09)The endocannabinoid system is an important regulator of the nervous, neuroendocrine, and immune systems, thus representing a novel therapeutic target for stress-related neuroinflammatory and psychiatric disorders. However, ...