Browsing Pharmacology & Therapeutics by Author "Butler, Ryan K."
Now showing items 1-4 of 4
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Endocannabinoid-mediated enhancement of fear-conditioned analgesia in rats: Opioid receptor dependency and molecular correlates
Butler, Ryan K.; Rea, Kieran; Lang, Yvonne; Gavin, Aisling M.; Finn, David P. (International Association for the Study of Pain, 2008-12)The opioid and endocannabinoid systems mediate analgesia expressed upon re-exposure to a contextually aversive stimulus (fear-conditioned analgesia; FCA), and modulate the mitogen-activated protein kinase (MAPK) pathway. ... -
Fear-induced suppression of nociceptive behaviour and activation of signal transduction molecules in the rat periaqueductal grey: role of fatty acid amide hydrolase.
Butler, Ryan K.; Ford, Gemma K.; Hogan, Michelle; Roche, Michelle; Doyle, Karen M.; Kelly, John P.; Finn, David P. (Sage, 2011-09-17)The endocannabinoid system regulates nociception and aversion and mediates fear-conditioned analgesia (FCA). We investigated the effects of the fatty acid amide hydrolase (FAAH) inhibitor URB597, which inhibits the catabolism ... -
Molecular and electrophysiological changes in the prefrontal cortex-amygdala-dorsal periaqueductal grey pathway during persistent pain state and fear-conditioned analgesia
Butler, Ryan K.; Finn, David P. (Elsevier, 2011-10)Fear-conditioned analgesia (FCA) is the reduction in pain responding which is expressed upon re-exposure to a context previously paired with an aversive stimulus. Projections along the prefrontal cortex (PFC)¿amygdala¿dorsal ... -
Stress-induced analgesia.
Butler, Ryan K.; Finn, David P. (Butler, R. K. & Finn, D.P. (2009). Stress-induced analgesia. Progress in Neurobiology, 88, 184-202., 2009)For over 30 years, scientists have been investigating the phenomenon of pain suppression upon exposure to unconditioned or conditioned stressful stimuli, commonly known as stress-induced analgesia. These studies have ...