Browsing School of Medicine by Author "Science Foundation Ireland"
Now showing items 1-3 of 3
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The impact of occlusion location and bridging therapy in patients affected by acute ischemic stroke in determining the total number of passes required to remove the clot and the final revascularization outcome
Rossi, Rosanna; Fitzgerald, Seán; Mereuta, Oana Madalina; Douglas, Andrew; Pandit, Abhay; Szikora, István; Tsivgoulis, Georgios; Psychogios, Klearchos; Murphy, Blathnaid; Brennan, Paul; Power, Sarah; O'Hare, Alan; Thornton, John; Rentzos, Alexandros; Tatlisumak, Turgut; Doyle, Karen M. (WFITN (World Federation of Interventional and Therapeutic Neuroradiology), 2019-10-21)Purpose Our purpose was to assess the impact of occlusion location in patients suffering from Acute Ischemic Stroke (AIS) on the total number of passes (attempts) necessary to retrieve the clot and on final revascularization ... -
Inhibition by Anandamide of 6-Hydroxydopamine-Induced Cell Death in PC12 Cells
Mnich, Katarzyna; Finn, David P.; Dowd, Eilis; Gorman, Adrienne M. (2010)6-hydroxydopamine (6-OHDA) is a selective neurotoxin that is widely used to investigate cell death and protective strategies in models of Parkinson's disease. Here, we investigated the effects of the endogenous cannabinoid, ... -
Pharmacological inhibition of endocannabinoid degradation modulates the expression of inflammatory mediators in the hypothalamus following an immunological stressor
Kerr, D.M.; Burke, N.N.; Ford, Gemma K.; Harhen, Brendan; Egan, Laurence J.; Finn, David P.; Roche, Michelle (Elsevier, 2011-09)The endocannabinoid system is an important regulator of the nervous, neuroendocrine, and immune systems, thus representing a novel therapeutic target for stress-related neuroinflammatory and psychiatric disorders. However, ...