Browsing School of Medicine by Subject "HIGH-ANXIETY RATS"
Now showing items 1-2 of 2
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Enhanced nociceptive responding in two rat models of depression is associated with alterations in monoamine levels in discrete brain regions
(2010)Altered pain responding in depression is a widely recognized but poorly understood phenomenon The present study investigated nociceptive responding to acute (thermal and mechanical) and persistent (inflammatory) noxious ... -
Impaired endocannabinoid signalling in the rostral ventromedial medulla underpins genotype-dependent hyper-responsivity to noxious stimuli
(International Association for the Study of Pain, 2014-01)Pain is both a sensory and an emotional experience, and is subject to modulation by a number of factors including genetic background modulating stress/affect. The Wistar-Kyoto (WKY) rat exhibits a stress-hyper-responsive ...