Browsing School of Medicine by Author "|~|"
Now showing items 21-40 of 89
-
Curriculum development for sustainable civic engagement
Boland, Josephine (Educational Developers of Ireland Network, 2013)Capacity building both for students and for community partners is an explicit goal for one particular teaching and learning innovation in Irish higher education. In addition to offering the opportunity to apply ... -
Design of a smartphone application with integrated Functional Electrical Stimulation (FES) treatment randomization and On-The-Fly Stimulus Parameter Adjustment for streamlining the clinical evaluation of FES protocols
Sweeney, D.; Corley, Gavin; Browne, P.; Burridge, J.H.; Quinlan, Leo R.; Ó Laighin, Gearóid (OMICS International, 2016-03-14)The clinical application of Functional Electrical Stimulation (FES) has evolved over the last five decades. However, the use of the Randomized Control Trial (RCT) methodology in evaluating the clinical effectiveness of new ... -
Detection of ROS induced proteomic signatures by mass spectrometry
McDonagh, Brian (Frontiers Media, 2017)Reversible and irreversible post-translational modifications ( PTMs) induced by endogenously generated reactive oxygen species (ROS) in regulatory enzymes and proteins plays an essential role in cellular signaling. Almost ... -
Distribution of tract deficits in schizophrenia
Cannon, Dara (BioMed Central, 2014-04-02)Background: Gray and white matter brain changes have been found in schizophrenia but the anatomical organizing process underlying these changes remains unknown. We aimed to identify gray and white matter volumetric changes ... -
Do general practitioners prescribe more antimicrobials when the weekend comes?
Tandan, Meera; Duane, Sinead; Vellinga, Akke (SpringerOpen, 2015-11-24)Inappropriate antimicrobial prescribing contributes to the global spread of antimicrobial resistance. The pending weekend with changed availability of general practitioners (GP) and increased patient concern may increase ... -
The effect of pain on cognitive function: a review of clinical and preclinical research.
Moriarty, Orla; McGuire, Brian E.; Finn, David P. (2011)Cognitive impairment is commonly associated with the pain experience. This impairment represents a major obstacle to daily activities and rehabilitation, especially in the chronic pain population. Here we review clinical ... -
Effects of arterial cannulation stress on regional cerebral blood flow in major depressive disorder
Savitz, J,Nugent, AC,Cannon, DM,Carlson, PJ,Davis, R,Neumeister, A,Rallis-Frutos, D,Fromm, S,Herscovitch, P,Drevets, WC (Nature Publishing Group, 2012)Individuals with major depressive disorder (MDD) display abnormal neurophysiological responses to psychological stress but little is known about their neurophysiological responses to physiological stressors. Using [O-15]-H2O ... -
Effects of Gamma Irradiation and Pasteurization on the Nutritive Composition of Commercially Available Animal Diets
Caulfield, Catherine D.; Kelly, John P. (2008)Gamma radiation is used to sterilize diets for specific pathogen-free (SPF) animals. Because a gamma-irradiated diet was linked to leukoencephalomyelopathy in SPF cats, we investigated the effects of 'typical' (28.9-34.3 ... -
The efficacy of mindfulness-based interventions in primary care: a meta-analytic review
Demarzo, Marcelo M.P.; Montero-Marin, Jesús; Cuijpers, Pim; Zabaleta-del-Olmo, Edurne; Mahtani, Kamal R.; Vellinga, Akke; Vicens, Caterina; López-del-Hoyo, Yolanda; García-Campayo, Javier (Annals of Family Medicine, 2015-07-16)PURPOSE Positive effects have been reported after mindfulness-based interventions (MBIs) in diverse clinical and nonclinical populations. Primary care is a key health care setting for addressing common chronic conditions, ... -
The endocannabinoid system and emotional processing: pathophysiology and therapeutic potential.
Finn, David P. (SAGE, 2012-01)Although the pharmacological and medicinal properties of the plant Cannabis sativa have long been known and appreciated, the discovery of the endocannabinoid system began with the isolation of [delta]9-tetrahydrocannabinol ... -
Endoscopic resection of nasopharyngeal angiofibroma: The role of radio-frequency coblation
Ali, Rohana; Keogh, Ivan; Lang, John (PagePress, 2011-08-29)Nasopharyngeal angiofibromas are histologically benign but locally aggressive vascular tumors that can result in major morbidity and mortality. They exclusively affect adolescent male and are rare in patients older than ... -
Enhanced nociceptive responding in two rat models of depression is associated with alterations in monoamine levels in discrete brain regions
Burke, N.N.; Hayes, E; Calpin, P; Kerr, DM; Moriarty, Orla; Finn, David P.; Roche, Michelle (2010)Altered pain responding in depression is a widely recognized but poorly understood phenomenon The present study investigated nociceptive responding to acute (thermal and mechanical) and persistent (inflammatory) noxious ... -
Enlarging neck masses in the elderly - Histological and surgical considerations.
O'Sullivan MD, McAnena KS, Egan C, Waters PS, McCann PJ, Kerin MJ (2013)INTRODUCTION: Anaplastic carcinoma of the thyroid is a rare but aggressive malignancy which can present with a rapidly enlarging neck mass or compressive sequelae of cough, dyspnoea, dysphagia and hoarseness. Treatment of ... -
Epidemiology of gestational diabetes mellitus according to IADPSG/WHO 2013 criteria among obese pregnant women in Europe
Egan, A. M.; Vellinga, Akke; Dunne, Fidelma (Springer Verlag, 2016-08-29)Accurate prevalence estimates for gestational diabetes mellitus (GDM) amongst pregnant women in Europe are lacking due to the use of a multitude of diagnostic criteria and screening strategies in both high-risk women and ... -
An evaluation of MyAction, a community-based lifestyle and medical risk factor modification programme, in women with prior gestational diabetes mellitus: study protocol for a randomised controlled trial
Infanti, Jennifer J.; Dunne, Fidelma P.; Gillespie, Paddy; Glynn, Liam G.; Noctor, Eoin; Newell, John; McGuire, Brian E.; O'Dea, Angela (BioMed Central, 2013-05-02)Universal screening using the International Association of Diabetes and Pregnancy Study Groups (IADPSG) criteria has identified a prevalence of gestational diabetes mellitus (GDM) of 12.4% in women living in Ireland. Women ... -
Evaluation of the Finis Swimsense (R) and the Garmin Swim (TM) activity monitors for swimming performance and stroke kinematics analysis
Mooney, Robert; Quinlan, Leo R.; Corley, Gavin; Godfrey, Alan; Osborough, Conor; Ó Laighin, Gearóid (Public Library of Science, 2017-02-08)Aims The study aims were to evaluate the validity of two commercially available swimming activity monitors for quantifying temporal and kinematic swimming variables. Methods Ten national level swimmers (5 male, 5 female; ... -
Excuse me: teaching junior doctors to speak up.
O'Connor, Paul; Byrne, Dara; O'Dea, Angela (SAGE Journals, 2013)A consistent finding in healthcare is that juniors are unwilling to 'speak up' to seniors. Training designed to encourage junior doctors to speak up was designed, delivered, and evaluated. The training was constructed ... -
Exploring experiences of delayed prescribing and symptomatic treatment for urinary tract infections among general practitioners and patients in ambulatory care: a qualitative study
Duane, Sinead; Beatty, Paula; Murphy, Andrew W.; Vellinga, Akke (MDPI (Multidisciplinary Digital Publishing Institute), 2016-08-15)"Delayed or back up" antibiotic prescriptions and "symptomatic" treatment may help to reduce inappropriate antibiotic prescribing for Urinary Tract Infections (UTI) in the future. However, more research needs to be conducted ... -
Free water elimination and mapping from diffusion tensor imaging (DTI) in chronic schizophrenia
Colgan, Niall; O'Reilly, David; Holleran, Laurena; Ahmed, Mohamed; McDonald, Colm; Cannon, Dara M. (NUI Galway, 2017-06-11)Diffusion tensor imaging (DTI) acquisitions allows the comparison of diffusion characteristics in vivo and gives a unique insight into tissue structure and pathology. However, a limitation of DTI post-processing is the ... -
Gender-specific abnormalities in the serotonin transporter system in panic disorder
Cannon, Dara (Cambridge University Press, 2013)The central serotonergic system has been implicated in the pathophysiology of panic disorder (PD) by evidence of abnormally elevated serotonin-turnover, reduced pre- and post-synaptic 5-HT(1A-)receptor sensitivity and ...