Browsing School of Medicine by Title
Now showing items 311-330 of 337
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Supraspinal transient receptor potential subfamily V member 1 (TRPV1) in pain and psychiatric disorders
(Karger, 2015)The transient receptor potential subfamily V member 1 (TRPV1) belongs to the diverse transient receptor potential (TRP) family of cation channels. It was first characterized in primary afferent fibres as a receptor for ... -
Surgical checklists: the human factor
(2013)Surgical checklists has been shown to improve patient safety and teamwork in the operating theatre. However, despite the known benefits of the use of checklists in surgery, in some cases the practical implementation has ... -
A systematic review of 7 years of research on entrustable professional activities in graduate medical education, 2011–2018
(Wiley, 2019-01-04)Purpose This review aimed to synthesise some of the extant work on the use of entrustable professional activities (EPAs) for postgraduate physicians, to assess the quality of the work and provide direction for future ... -
A systematic review of interventions to foster physician resilience
(BMJ Publishing Group, 2018-02-21)This review aimed to synthesise the literature describing interventions to improve resilience among physicians, to evaluate the quality of this research and to outline the type and efficacy of interventions implemented. ... -
A systematic review of measurement tools for the proactive assessment of patient safety in general practice
(Lippincott, Williams & Wilkins, 2017-04-04)Background Primary care physicians have reported a difficulty in understanding how best to measure and improve patient safety in their practices. Objectives The aims of the study were to identify measures of patient ... -
A systematic review of patient complaints about general practice
(Oxford University Press (OUP), 2019-11-19)Objective This review aimed to synthesize the extant research on complaints in general practice. Methods Five electronic databases were searched: Medline, Web of Science, CINAHL, PsycINFO and Academic Search Complete. ... -
A systematic review of patient complaints about general practice.
(Oxford University Press (OUP), 2019-11-19)Health care complaints are an underutilized resource for quality and safety improvement. Most research on health care complaints is focused on secondary care. However, there is also a need to consider patient safety in ... -
A systematic review of the use of positive deviance approaches in primary care
(Oxford University Press, 2021-11-25)Abstract Background: The Positive Deviance (PD) approach focuses on identifying and learning from those who demonstrate exceptional performance despite facing similar resource constraints to others. Recently, it has been ... -
Systemic chemokine levels in breast cancer patients and their relationship with circulating menstrual hormones
(Springer, 2008-06-04)Introduction The chemokines Stromal Cell-Derived Factor-1 alpha (SDF-1 alpha/CXCL12) and Monocyte Chemotactic Protein-1 (MCP-1/CCL2) have been implicated in breast cancer progression. We recently reported elevated systemic ... -
Teaching and learning through civic engagement: prospects for sustainability in teacher education
(2010)This paper considers the prospects for sustainable service/community based learning as an element of a civic engagement strategy within the context of teacher education. It draws on findings of a study of the policy, ... -
Therapeutic effect of neurotrophin-3 treatment in an injectable collagen scaffold following rat spinal cord hemisection injury
(American Chemical Society, 2016-08-01)Spinal cord injury (SCI) patients display varying quantities of spinal cord tissue damage with injuries that present as complete, incomplete or compressive. One theory proposed to repair the injured spinal cord and regain ... -
These shoes are made for walking: sensitivity performance evaluation of commercial activity monitors under the expected conditions and circumstances required to achieve the international daily step goal of 10,000 steps
(Public Library of Science, 2016-05-11)IntroductionPhysical activity is a vitally important part of a healthy lifestyle, and is of major benefit to both physical and mental health. A daily step count of 10,000 steps is recommended globally to achieve an appropriate ... -
Third-party allogeneic mesenchymal stromal cells prevent rejection in a pre-sensitized high-risk model of corneal transplantation
(Frontiers Media, 2018-11-20)High-risk cornea transplant recipients represent a patient population with significant un-met medical need for more effective therapies to prevent immunological graft rejection due to heightened anti-donor immune response. ... -
Time and region-dependent manner of increased brain derived neurotrophic factor and TrkB in rat brain after binge-like methamphetamine exposure
(Elsevier, 2019-11-03)Methamphetamine (MA), a synthetic derivate of amphetamine, has become a major drug of abuse worldwide. This study investigated the effect of binge-like MA dosing (4 x 4 mg/kg, s.c., 2 h (h) apart) at a range of different ... -
TNF-a/IL-1ß-licensed mesenchymal stromal cells promote corneal allograft survival via myeloid cell-mediated induction of Foxp3+ regulatory T cells in the lung.
(Federation of American Society of Experimental Biology (FASEB), 2019-05-20)Mesenchymal stromal cells (MSCs) have shown promise as a therapy for immune-mediated disorders, including transplant rejection. Our group previously demonstrated the efficacy of pretransplant, systemic administration of ... -
A toolkit for improving hand hygiene compliance in intensive care
(National University of Ireland Galway, 2020-10-15)A toolkit to help intensive care units to identify how they can improve hand hygiene compliance. -
Ulk4 regulates GABAergic signaling and anxiety-related behavior
(Springer Nature, 2018-02-02)Excitation/inhibition imbalance has been proposed as a fundamental mechanism in the pathogenesis of neuropsychiatric and neurodevelopmental disorders, in which copy number variations of the Unc-51 like kinase 4 (ULK4) gene ... -
Urinary sodium and potassium, and risk of ischemic and hemorrhagic stroke (INTERSTROKE): A case–control study
(Oxford University Press, 2020-11-16)Although low sodium intake (3·5g/day) are proposed as public health interventions to reduce stroke risk, there is uncertainty about the benefit and feasibility of this combined recommendation on prevention of stroke and ... -
Using mobile phones to collect patient data: lessons learned from the SIMPle study
(JMIR Publications, 2017-04-25)Background: Mobile phones offer new opportunities to efficiently and interactively collect real-time data from patients with acute illnesses, such as urinary tract infections (UTIs). One of the main benefits of using mobile ... -
Using qualitative insights to change practice: exploring the culture of antibiotic prescribing and consumption for urinary tract infections
(BMJ Publishing Group, 2016-01-11)Objectives: The aim of this paper is to explore the culture of antibiotic prescribing and consumption in the community for urinary tract infections (UTI) from the perspective of the general practitioners (GPs) and community ...