Browsing College of Medicine, Nursing and Health Sciences by Author "|~|"
Now showing items 1-20 of 171
-
11q13 is a susceptibility locus for hormone receptor positive breast cancer.
Kerin, Michael J.; Miller, Nicola (Wiley, 2012-07)A recent two-stage genome-wide association study (GWAS) identified five novel breast cancer susceptibility loci on chromosomes 9, 10, and 11. To provide more reliable estimates of the relative risk associated with these ... -
The 5-HT1A receptor and 5-HT transporter in temporal lobe epilepsy
Cannon, Dara (2013)Objective: To study 5-HT transport and 5-HT1A receptors in temporal lobe epilepsy (TLE) and depression.Methods: Thirteen patients had PET with [C-11]DASB for 5-HTT and [F-18]FCWAY for 5-HT1A receptor binding, MRI, and ... -
6-iodonordihydrocapsaicin
Roche, Michelle; Finn, David P. (2009)6-Iodonordihydrocapsaicin was first synthesized by Giovanni Appendino at the Department of Chemical, Food, Pharmaceutical and Pharmacological Sciences (DiSCAFF), Novara, Italy, while developing a series of halogenated ... -
Altered neuropathic pain behaviour in a rat model of depression is associated with changes in inflammatory gene expression in the amygdala
Burke, Nikita N.; Geoghegan, E.; Moriarty, Orla; Finn, David P.; Kerr, Daniel M.; Roche, Michelle (Wiley, 2013-08-29)The association between chronic pain and depression is widely recognized, the comorbidity of which leads to a heavier disease burden, increased disability and poor treatment response. This study examined nociceptive ... -
Anandamide modulation of endotoxin-induced inflammation
Kerr, Daniel M.; Henry, Rebecca; Roche, Michelle (OMICS International, 2013-12-20)The endocannabinoid system is comprised of the CB1 and CB2 receptors, the naturally occurring endogenous ligands, anandamide (AEA) and 2-arachidonyl glycerol (2-AG); and the enzymes involved in their synthesis and ... -
Antimicrobial management and appropriateness of treatment of urinary tract infection in general practice in Ireland
Vellinga, Akke; Cormican, Martin; Hanahoe, Belinda; Murphy, Andrew W. (2011)ABSTRACT: BACKGROUND: Urinary tract infections (UTIs) are the second most common bacterial infections in general practice and a frequent indication for prescription of antimicrobials. Increasing concern about the association ... -
Appendix 1: Nutrition behaviours and outcomes: a special analysis of the HBSC survey as part of the implementation of the National Strategy for Research and Data on Children's Lives, 2011-2016.
Callaghan, Mary; Nic Gabhainn, Saoirse (Department of Children and Youth Affairs, 2013) -
Approaches to rigour in qualitative case study research
Houghton, Catherine E.; Casey, Dympna; Murphy, Kathy (RCN Publishing, 2012-03-01)Aim - To provide examples of a qualitative multiple case study to illustrate the specific strategies that can be used to ensure the credibility, dependability, confirmability and transferability of a study. Background ... -
The association of white matter volume in psychotic disorders with genotypic variation in NRG1, MOG and CNP: a voxel-based analysis in affected individuals and their unaffected relatives
Cannon, Dara (Nature Publishing Group, 2012)We investigated the role of variation in putative psychosis genes coding for elements of the white matter system by examining the contribution of genotypic variation in three single-nucleotide polymorphisms (SNPs) neuregulin ... -
ATLANTIC DIP: simplifying the follow-up of women with previous gestational diabetes
O'Dea, Angela (European Society of Endocrinology, 2013)Objective: Previous gestational diabetes (GDM) is associated with a significant lifetime risk of type 2 diabetes. In this study, we assessed the performance of HbA1c and fasting plasma glucose (FPG) measurements against ... -
Behaviour change techniques targeting both diet and physical activity in type 2 diabetes: A systematic review and meta-analysis
Cradock, Kevin A.; Ó Laighin, Gearóid; Finucane, Francis M.; Gainforth, Heather L.; Quinlan, Leo R.; Martin Ginis, Kathleen A. (BioMed Central, 2017-02-08)Background: Changing diet and physical activity behaviour is one of the cornerstones of type 2 diabetes treatment, but changing behaviour is challenging. The objective of this study was to identify behaviour change techniques ... -
Behavioural, neurochemical and neuroendocrine effects of the endogenous beta-carboline harmane in fear-conditioned rats
Smith, Karen L.; Ford, Gemma K.; Finn, David P. (2012)The putative endogenous imidazoline binding site ligand harmane enhances neuronal activation in response to psychological stress and alters behaviour in animal models of anxiety and antidepressant efficacy. However, the ... -
Brain CB2 receptors: Implication for Neuropsychiatric disorders
Roche, Michelle; Finn, David P. (2010)Although previously thought of as the peripheral cannabinoid receptor, it is now accepted that the CB2 receptor is expressed in the central nervous system on microglia, astrocytes and subpopulations of neurons. Expression ... -
Bridging the Digital Disconnect for Parents: Exploring Parents Views on Using Technology to Promote Young People s Mental Health.
Clarke, AM; Kuosmanen, T; Chambers, D; Barry, Margaret M. (HPRC & Inspire Ireland and Young and Well CRC, 2013)Bridging the Digital Disconnect is a three-year program of research that aims to develop online mental health anddigital literacy resources for adults - including parents, teachers, youth workers, social workers, general ... -
Bridging the Digital Disconnect: Exploring Youth, Education, Health and Mental Health Professionals Views on Using Technology to Promote Young People s Mental Health
Clarke, AM; Kuosmanen, T; Chambers, D; Barry, Margaret M. (HPRC, 2014)Bridging the Digital Disconnect is a three-year program of research that aims to develop online resources for adults, including parents, youth workers, education, health and mental health professionals who wish to ... -
Bullying among schoolchildren in Ireland. HBSC Ireland Research Factsheet No. 8.
Callaghan, Mary (HBSC Ireland, 2010-05)HBSC Ireland 2010 has found that 24.3% of schoolchildren in Ireland report having been bullied (25.5% of boys and 23% of girls). This figure has remained stable since 2006 (24.5%). The percentages of boys and girls being ... -
Bullying others among schoolchildren in Ireland. HBSC Ireland Research Factsheet No. 9.
Callaghan, Mary (HBSC Ireland, 2012)HBSC Ireland 2010 has found that 16.5% of schoolchildren in Ireland report having bullied others at school (22.3% of boys and 10.4% of girls), representing a decrease since 2006 (22.0%). The percentage of boys that have ... -
Career choices of today's medical students: where does surgery rank?
Kerin, Michael J. (Springer, 2013-11-15)The national junior doctor recruitment crisis prompts an appraisal of medical student attitudes to different career pathways. The purpose of this study was to perform a national review of surgical career intentions of Irish ... -
'Choose Safety'. An evaluation of a Health and Safety module for use in secondary schools. Health Promotion Research Centre, NUI, Galway
Hodgins, Margaret; Hogan, Victoria; Galvin, Marie (Health Promotion Research Centre, NUI Galway, 2009-01)The overall aim of this project was to comprehensively evaluate the pilot of the 'Choose Safety' module developed by the H.S.A. The module is a teaching and learning pack for post-primary students. The main objectives of ... -
Chronic administration of amitriptyline differentially alters neuropathic pain-related behaviour in the presence and absence of a depressive-like phenotype
Burke, Nikita N.; Finn, David P.; Roche, Michelle (Elsevier, 2015-02)Chronic pain and depression share a complex, reciprocal relationship. Furthermore, in addition to treating depression, antidepressants such as amitriptyline are a first-line treatment for chronic pain conditions, indicating ...