Browsing College of Medicine, Nursing and Health Sciences by Title
Now showing items 83-102 of 853
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Cell viability in three ex vivo rat models of spinal cord injury
(Wiley, 2018-11-11)Spinal cord injury (SCI) is a devastating disorder that has a poor prognosis of recovery. Animal models of SCI are useful to understand the pathophysiology of SCI and the potential use of therapeutic strategies for human ... -
Central CB2 receptors in inflammation-driven neurodegeneration: dysregulation and therapeutic potential
(Medknow Publications, 2016-10-19)In recent times there has been an intensification of interest in the pathological role of neuroinflammation in neurodegenerative disease. Neuroprotective strategies to slow, halt or reverse neurodegeneration have not proven ... -
Changing antibiotic prescribing in General Practice – The results of the SIMPle process evaluation
(Sciedu Press, 2017)Objective: The Supporting the Improvement and Management of Prescribing for Urinary Tract Infections (SIMPle) study, a cluster randomized trial, sought to improve the quality of antibiotic prescribing for Urinary Tract ... -
Characterisation of peroxisome proliferator-activated receptor signalling in the midbrain periaqueductal grey of rats genetically prone to heightened stress, negative affect and hyperalgesia
(Elsevier, 2016-12-01)The stress-hyperresponsive Wistar-Kyoto (WRY) rat strain exhibits a hyperalgesic phenotype and is a useful genetic model for studying stress-pain interactions. Peroxisome proliferator-activated receptor (PPAR) signalling ... -
Characterization of the affective component of acute postoperative pain associated with a novel rat model of inguinal hernia repair pain
(Wiley, 2015-12-10)Aims: Acute postoperative pain remains a significant healthcare issue. Historically, the assessment of postoperative pain in rodents has relied on evoked withdrawal or reflexive measures. Using a recently developed, ... -
Child protection role of community nurses: the views of Public Health Nurses in Ireland
(Redactive Publishing Limited on behalf of Unite and CPHVA, 2011-11)Public health nurses in Ireland are generalist practitioners with a wide range of roles that address the needs of clients in the community across their lifespan. Child protection is one of many of the roles of Irish ... -
Child well-being: children's, parents' and teachers' perceptions.
(National Institute of Health Sciences, 2008-10)That chldren's lives be better understood is a necessary contributing step to the development of child centred quality supports, services and policies and it would appear logical that actively seeking out children's voices ... -
Children photographing well-being: facilitating participation in research
(Wiley, 2006-09)Children aged 8-12 years took 723 photographs representing well-being. Another group of children categorised the photographs, identified what was missing and discussed their inter-relationships. The largest categories were ... -
Children's exposure to ultraviolet radiation - a risk profile for future skin cancers in Ireland
(Institute of Public Health in Ireland, 2020-06)Key points Why has this report been developed? Excessive exposure to ultraviolet (UV) radiation, sunburn and sunbed use in childhood are risk factors for developing skin cancer in adult life. This report presents data ... -
Childrens', parents' and teachers' perceptions of child wellbeing.
(2007)Purpose - The purpose of this paper is to present an exploration of parents', teachers' and childrens' perspectives on children's understanding of wellbeing with the aim of illuminating and comparing the conceptualisation ... -
Children’s participation in school: a cross-sectional study of the relationship between school environments, participation and health and well-being outcomes
(BMC, 2014-09-17)Background: Schools are a key setting for health promotion and improvement activities and the psycho-social environment of the school is an important dimension for promoting the health and well-being of children. The ... -
Chlamydia trachomatis infection and sexual behaviour among female students attending higher education in the Republic of Ireland
(2009)Background There are no prevalence data on Chlamydia trachomatis relating to female students attending higher education available for the Republic of Ireland. This information is required to guide on the necessity for ... -
Chondrocytes derived from mesenchymal stromal cells and induced pluripotent cells of patients with familial osteochondritis dissecans exhibit an endoplasmic reticulum stress response and defective matrix assembly
(Wiley, 2016-07-07)Familial osteochondritis dissecans (FOCD) is an inherited skeletal defect characterized by the development of large cartilage lesions in multiple joints, short stature, and early onset of severe osteoarthritis. It is ... -
'Choose Safety'. An evaluation of a Health and Safety module for use in secondary schools. Health Promotion Research Centre, NUI, Galway
(Health Promotion Research Centre, NUI Galway, 2009-01)The overall aim of this project was to comprehensively evaluate the pilot of the 'Choose Safety' module developed by the H.S.A. The module is a teaching and learning pack for post-primary students. The main objectives of ... -
Chronic administration of amitriptyline differentially alters neuropathic pain-related behaviour in the presence and absence of a depressive-like phenotype
(Elsevier, 2015-02)Chronic pain and depression share a complex, reciprocal relationship. Furthermore, in addition to treating depression, antidepressants such as amitriptyline are a first-line treatment for chronic pain conditions, indicating ... -
Chronic administration of buprenorphine in combination with samidorphan produces sustained effects in olfactory bulbectomised rats and Wistar-Kyoto rats
(SAGE Publications, 2019-09-12)Background: The combination of buprenorphine, a partial mu-opioid receptor agonist and a functional kappa-opioid receptor antagonist, with samidorphan, a functional mu-opioid receptor antagonist, is being developed as an ... -
Chronic fluoxetine treatment attenuates stressor-induced changes in temperature, heart rate, and neuronal activation in the olfactory bulbectomised rat
(2007)The olfactory bulbectomized (OB) rat is a well characterized animal model that exhibits a number of behavioural and neurochemical changes that have relevance to clinical depression. Hyperactivity in the open field is the ... -
Circuitry underlying regulation of the serotonergic system by swim stress
(Society for Neuroscience, 2003-02-01)The dorsal raphe nucleus (DR)–serotonin (5-HT) system has been implicated in depression and is dramatically affected by swim stress, an animal model with predictive value for antidepressants. Accumulating evidence implicates ... -
Circulating MicroRNAs in cancer
(Humana Press, 2016-11-09)It is believed that microRNAs have potential as circulating biomarkers of disease, however successful clinical implementation remains a challenge. This chapter highlights broad variations in approaches to microRNA analysis ...