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    • Dynamic actuation enhances transport and extends therapeutic lifespan in an implantable drug delivery platform 

      Whyte, William; Goswami, Debkalpa; Wang, Sophie X.; Fan, Yiling; Ward, Niamh A.; Levey, Ruth E.; Beatty, Rachel; Robinson, Scott T.; Sheppard, Declan; O’Connor, Raymond; Monahan, David S.; Trask, Lesley; Mendez, Keegan L.; Varela, Claudia E.; Horvath, Markus A.; Wylie, Robert; O’Dwyer, Joanne; Domingo-Lopez, Daniel A.; Rothman, Arielle S.; Duffy, Garry P.; Dolan, Eimear B.; Roche, Ellen T. (Nature Research, 2022-08-03)
      Fibrous capsule (FC) formation, secondary to the foreign body response (FBR), impedes molecular transport and is detrimental to the long-term efficacy of implantable drug delivery devices, especially when tunable, temporal ...