Browsing National Centre for Biomedical Engineering Science by Title
Now showing items 48-67 of 83
-
Incompressible moving boundary flows with the finite volume particle method
(Elsevier, 2010-03-24)Mesh-free methods offer the potential for greatly simplified modeling of flow with moving walls and phase interfaces. The finite volume particle method (FVPM) is a mesh-free technique based on interparticle fluxes which ... -
Interaction of cell culture with composition effects on the mechanical properties of polycaprolactone-hydroxyapatite scaffolds fabricated via selective laser sintering (SLS)
(Elsevier, 2012)In the current study PCL/HA composites were fabricated using SLS as two- and three-dimensional lattice structures and exposed to a cellular component (MC 313 osteoblast-like cells). The main aims were to determine the ... -
Isolation and characterization of the bovine Stearoyl-CoAdesaturase promoter and analysis of polymorphisms in the promoter region in dairy cows
(Springer, 2005-03)Conjugated linoleic acid (CLA) in milk arises through microbial biohydrogenation of dietary polyunsaturated fatty acids (PUFA) in the rumen, and by the action of mammary Stearoyl-CoA desaturase (Scd). A large variation ... -
Kinase Inhibitor against Quiescent and Proliferating CLL Cells
(2011-07-18)In chronic lymphocytic leukemia (CLL) the proliferation rate and resistance to drug-induced apoptosis are recognized as important factors in the outcome of treatment. In this study, we assess the activity and the mechanism ... -
Laser sintering for the fabrication of tissue engineering scaffolds
(Springer Science+Business Media, 2012)Laser sintering (LS) utilises a laser to sinter powder particles. A volumetric model is sliced and processedcross section by cross section to create a physical part. In theory, all powdered materials are suitable forsintering; ... -
Linear regression for estimating bladder volume with voltage signals
(IEEE, 2018-11-08)Urinary incontinence is a common condition that can severely impact the lives of those who have it. Bladder volume monitoring solutions that exploit the electrical differences of different tissues in the pelvis have the ... -
Long-term exposure of CdTe quantum dots on PC12 cellular activity and the determination of optimum non-toxic concentrations for biological use
(2010)Background: The unique and tuneable photonic properties of Quantum Dots (QDs) have made them potentially useful tools for imaging biological entities. However, QDs though attractive diagnostic and therapeutic tools, have ... -
Mesenchymal stem cells and osteoarthritis: remedy or accomplice?
(Mary Ann Liebert, Inc., 2010-10)Multipotent mesenchymal stromal or stem cells (MSCs) are likely to be agents of connective tissue homeostasis and repair. Because the hallmark of osteoarthritis (OA) is degeneration and failure to repair connective tissues ... -
Microscale flow structures measured downstream of a mechanical heart valve
(Trinity College Dublin, 2010-01-22) -
miRNA signature of unfolded protein response in H9c2 rat cardiomyoblasts
(2014)Background: Glucose and oxygen deprivation during ischemia is known to affect the homeostasis of the endoplasmic reticulum (ER) in ways predicted to activate the unfolded protein response (UPR). Activation of UPR signalling ... -
Models of flow-induced loading on blood cells in laminar and turbulent flow, with application to cardiovascular device flow
(Springer, 2007-08)Viscous shear stress and Reynolds stress are often used to predict hemolysis and thrombosis due to flow-induced stress on blood elements in cardiovascular devices. These macroscopic stresses are distinct from the true ... -
Modulation of human uterine smooth muscle cell collagen contractility by thrombin, Y-27632, TNF alpha and indomethacin
(Springer, 2009-01-08)Background: Preterm labour occurs in approximately 10% of pregnancies and is a major cause of infant morbidity and mortality. However, the pathways involved in regulating contractility in normal and preterm labour are ... -
Modulation of human uterine smooth muscle cell collagen contractility by thrombin, Y-27632, TNF alpha and indomethacin
(BioMed Central, 2009-01-08)Background: Preterm labour occurs in approximately 10% of pregnancies and is a major cause of infant morbidity and mortality. However, the pathways involved in regulating contractility in normal and preterm labour are not ... -
Multiclass SVM for bladder volume monitoring using electrical impedance measurements
(IEEE, 2018-11-08)Urinary incontinence is a common condition that impacts the quality of life from those who suffer from it. Electrical impedance measurements offer the potential for a non-invasive low-cost solution to monitor changes in ... -
Neuronal glycosylation differentials in normal, injured and chondroitinase-treated environments
(2012)Glycosylation is found ubiquitously throughout the central nervous system (CNS). Chondroitin sulphate proteoglycans (CSPGs) are a group of molecules heavily substituted with glycosaminoglycans (GAGs) and are found in the ... -
A note on the evaluation of a beta-casein variant in bovine breeds by allele-specific PCR and relevance to beta-casomorphin
(Teagasc; De Gruyter Open, 2008)Two genetic variants of the bovine beta-casein gene (A(1) and B) encode a histidine residue at codon 67, resulting in potential liberation of a bioactive peptide, beta-casomorphin, upon digestion. An allele-specific PCR ... -
Oxytocic plant cyclotides as templates for peptide G protein-coupled receptor ligand design
(National Academy Of Sciences Of The United States Of America, 2013-10-23)Cyclotides are plant peptides comprising a circular backbone and three conserved disulfide bonds that confer them with exceptional stability. They were originally discovered in Oldenlandia affinis based on their use in ... -
Periodic acid-Schiff's reagent assay for carbohydrates in a microtiter plate format
(2011)Microtiter plate colorimetric assays are widely used for analysis of carbohydrates and glycoconjugates. However, mucins are often not easily detected, as they have low neutral sugar content. We have adapted and optimised ... -
Permeable and Non-reflecting Boundary Conditions in SPH
(Wiley, 2009-11)Inflow and outflow boundary conditions are essential for the application of computational fluid dynamics to many engineering scenarios. In this paper we present a new boundary condition implementation that enables the ...