Browsing Research Institutes and Centres by Author "Coleman, Cynthia M."
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Biodistribution and retention of locally administered human mesenchymal stromal cells: Quantitative polymerase chain reaction–based detection of human DNA in murine organs
Creane, Michael; Howard, Linda; O'Brien, Timothy; Coleman, Cynthia M. (Elsevier, 2017-01-12)Background. Determining the distributive fate and retention of a cell therapy product after administration is an essential part of characterizing it's biosafety profile. Therefore, regulatory guidelines stipulate that ... -
Mesenchymal stem cells and osteoarthritis: remedy or accomplice?
Coleman, Cynthia M.; Curtin, Caroline; Barry, Frank; O'Flatharta, Cathal; Murphy, Mary (Mary Ann Liebert, Inc., 2010-10)Multipotent mesenchymal stromal or stem cells (MSCs) are likely to be agents of connective tissue homeostasis and repair. Because the hallmark of osteoarthritis (OA) is degeneration and failure to repair connective tissues ...