Browsing Research Institutes and Centres by Subject "Apoptosis"
Now showing items 1-3 of 3
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Effects of long-term exposure of gelatinated and non-gelatinated cadmium telluride quantum dots on differentiated PC12 cells
(BioMed Central, 2012-01-20)Background: The inherent toxicity of unmodified Quantum Dots (QDs) is a major hindrance to their use in biological applications. To make them more potent as neuroprosthetic and neurotherapeutic agents, thioglycolic acid ... -
miRNA signature of unfolded protein response in H9c2 rat cardiomyoblasts
(2014)Background: Glucose and oxygen deprivation during ischemia is known to affect the homeostasis of the endoplasmic reticulum (ER) in ways predicted to activate the unfolded protein response (UPR). Activation of UPR signalling ... -
Perk-dependent repression of miR-106b-25 cluster is required for ER stress-induced apoptosis
(2012)Activation of the unfolded protein response sensor PKR-like endoplasmic reticulum kinase (Perk) attenuates endoplasmic reticulum (ER) stress levels. Conversantly, if the damage is too severe and ER function cannot be ...