Now showing items 485-504 of 1311

    • Functional coupling of beta(3)-adrenoceptors and large conductance calcium-activated potassium channels in human uterine myocytes 

      Doheny, Helen C.; Lynch, Caoimhe M.; Smith, Terry; Morrison, John J. (Endocrine Society, 2005-07-02)
      Context: beta(3)-Adrenoreceptor modulation in human myometrium during pregnancy is linked functionally to myometrial inhibition. Maxi-K+ channels (BKCa) play a significant role in modulating cell membrane potential and ...
    • Future directions in managing aniridia-associated keratopathy 

      van Velthoven, Arianne J.H.; Utheim, Tor P.; Notara, Maria; Bremond-Gignac, Dominique; Figueiredo, Francisco C.; Skottman, Heli; Aberdam, Daniel; Daniels, Julie T.; Ferrari, Giulio; Grupcheva, Christina; Koppen, Carina; Parekh, Mohit; Ritter, Thomas; Romano, Vito; Ferrari, Stefano; Cursiefen, Claus; Lagali, Neil; LaPointe, Vanessa L.S.; Dickman, Mor M. (Elsevier, 2023-05-04)
      Congenital aniridia is a panocular disorder that is typically characterized by iris hypoplasia and aniridia-associated keratopathy (AAK). AAK results in the progressive loss of corneal transparency and thereby loss of ...
    • Future research in agile systems development: applying open innovation principles within the agile organisation 

      Conboy, Kieran; Morgan, Lorraine (Springer Verlag, 2010)
      A particular strength of agile approaches is that they move away from 'introverted' development and intimately involve the customer in all areas of development, supposedly leading to the development of a more innovative ...
    • Gamma band light stimulation in human case studies: Groundwork for potential Alzheimer's disease treatment 

      Jones, Marggie; McDermott, Barry; Oliveira, Bárbara Luz; O'Brien, Aoife; Coogan, Declan; Lang, Mark; Moriarty, Niamh; Dowd, Eilis; Quinlan, Leo; Mc Ginley, Brian; Dunne, Eoghan; Newell, David; Porter, Emily; Elahi, Muhammad Adnan; O' Halloran, Martin; Shahzad, Atif (IOS Press, 2019-05-27)
      It is known that proteins associated with Alzheimer's disease (AD) pathogenesis are significantly reduced by 40¿Hz entrainment in mice. If this were to translate to humans, verifying that such a light stimulus can induce ...
    • Gender and Childcare:Creating a space for 'womenandchildren' in Irish policy-making. 

      Carney, Gemma M. (2004)
      This paper grows from doctoral research on gender mainstreaming in the Republic of Ireland. Interviews with equality policy-makers revealed that initial investment in childcare, (£1m in 1993), was used by policy-makers to ...
    • Gendered impacts of extended working life on the health and economic wellbeing of older workers 

      Ní Léime, Áine; Ogg, Jim (Cambridge University Press, 2019-01-31)
      This special issue focuses on the gendered impact of extending working life on the health and economic wellbeing of older workers. Since research on this increasingly important area of policy interest is well developed in ...
    • Gene expression profiling identifies interferon signalling molecules and IGFBP3 in human degenerative annulus fibrosus 

      Kazezian, Zepur; Gawri, Rahul; Haglund, Lisbet; Ouellet, Jean; Mwale, Fackson; Tarrant, Finbarr; O’Gaora, Peadar; Pandit, Abhay; Alini, Mauro; Grad, Sibylle (Nature Publishing Group:, 2015-10-22)
      Low back pain is a major cause of disability especially for people between 20 and 50 years of age. As a costly healthcare problem, it imposes a serious socio-economic burden. Current surgical therapies fail to replace the ...
    • Gene prediction using the Self-Organizing Map: automatic generation of multiple gene models 

      McInerney, James O; Smith, Terry; Mahony, Shaun; Golden, Aaron (BioMed Central, 2005-03-05)
      Background: Many current gene prediction methods use only one model to represent protein-coding regions in a genome, and so are less likely to predict the location of genes that have an atypical sequence composition. It ...
    • Gene prediction using the Self-Organizing Map: automatic generation of multiple gene models 

      Mahony, Sean; Smith, Terry (2004-03-05)
      This work explores a new approach to gene-prediction, based on the Self-Organizing Map, which has the ability to automatically identify multiple gene models within a genome. The current implementation, named RescueNet, ...
    • Gene therapy in transplantation: Toward clinical trials 

      Ritter, Thomas (Thompson, 2009)
      The genetic modification of organs or cells is an attractive approach to protect allogeneic transplants from acute rejection and other complications. The transplant setting offers a unique opportunity to utilise ex vivo ...
    • Generating linked-data based domain-specific sentiment lexicons from legacy language and semantic resources 

      Vulcu, Gabriela; Buitelaar, Paul; Negi, Sapna; Pereira, Bianca; Arcan, Mihael; Coughlan, Barry; Sanchez, J. Fernando; Iglesias, Carlos A. (European Language Resources Association, 2014)
      We present a methodology for legacy language resource adaptation that generates domain-specific sentiment lexicons organized around domain entities described with lexical information and sentiment words described in the ...
    • Genetically Modified Mesenchymal Stem 

      Griffin, Matthew; Greiser, Udo; Barry, Frank; O'Brien, Timothy; Ritter, Thomas (2010-03)
      Adult mesenchymal stem cells (MSCs) are non-hematopoietic cells with multi-lineage potential to differentiate into various tissues of mesodermal origin. They can be isolated from bone marrow and other tissues and have the ...
    • GenomeSnip: Fragmenting the Genomic Wheel to augment discovery in cancer research 

      Kamdar, M; Iqbal, A; Saleem, M; Deus, H; Decker, S (2014)
      Cancer genomics researchers have greatly benefited from high-throughput technologies for the characterization of genomic alterations in patients. These voluminous genomics datasets when supplemented with the appropriate ...
    • GenomeSnip: Fragmenting the Genomic Wheel to augment discovery in cancer research 

      Kamdar, MR; Iqbal, A; Saleem, M; Deus, HF; Decker, S (ISCB, 2014-02-28)
      Cancer genomics researchers have greatly benefited from high-throughput technologies for the characterization of genomic alterations in patients. These voluminous genomics datasets when supplemented with the appropriate ...
    • Geographic Routing in Wireless Multimedia Sensor Networks 

      Shu, Lei; Hauswirth, Manfred (IEEE, 2008)
      In this paper, a -Phase geographic GreeTwody Forwarding (TPGF) routing algorithm is proposed in wireless multimedia sensor networks (WMSNs). TPGF is a pure geographic greedy forwarding routing algorithm, which does not ...
    • Ghrelin in the human myometrium 

      O'Brien, Margaret; Earley, Padraig; Morrison, John J.; Smith, Terry (BioMed Central Ltd, 2010-03-29)
      Ghrelin is a 28-amino acid octanolyated peptide, synthesised primarily in the stomach. It stimulates growth hormone release, food intake and exhibits many other diverse effects. Our group have previously determined that ...
    • Ghrelin in the human myometrium 

      Smith, Terry; O'Brien, Margaret; Morrison, John J. (2010)
      Background: Ghrelin is a 28-amino acid octanolyated peptide, synthesised primarily in the stomach. It stimulates growth hormone release, food intake and exhibits many other diverse effects. Our group have previously ...
    • Global biodiversity of the genus Ommastrephes (Ommastrephidae: Cephalopoda): an allopatric cryptic species complex 

      Fernández-Álvarez, Fernando Ángel; Braid, Heather E.; Nigmatullin, Chingis M.; Bolstad, Kathrin S. R.; Haimovici, Manuel; Sánchez, Pilar; Sajikumar, Kurichithara K.; Ragesh, Nadakkal; Villanueva, Roger (Oxford University Press (OUP), 2020-03-20)
      Cryptic speciation among morphologically homogeneous species is a phenomenon increasingly reported in cosmopolitan marine invertebrates. This situation usually leads to the discovery of new species, each of which occupies ...
    • Global gene expression analysis of the effects of Vinblastine on endothelial cells, when eluted from a thermo-responsive polymer 

      McLucas, Emily; Rochev, Yury; Carroll, W. M.; Smith, Terry (Wiley Online Library, 2006-06-30)
      In-stent restenosis remains a significant problem associated with bare metal stents. This drawback has prompted research into improving stent design and the development of novel coatings, including drug-eluting stents. A ...
    • GLobe: All-Ireland Programme for Immigrant Parents. Final Evaluation Report 

      Coen, Liam; Canavan, John (UNESCO Child and Family Research Centre, 2012-02)
      In 2007, the Child and Family Research Centre, NUI Galway, was commissioned by the PMC to evaluate Globe: All Ireland Programme for Immigrant Parents. From 2007 ¿ 2009 a number of interim evaluation reports were submitted ...