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The cost-effectiveness of the SPHERE intervention for the secondary prevention of coronary heart disease

ARAN - Access to Research at NUI Galway

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dc.contributor.author Gillespie, Paddy en
dc.contributor.author O'Shea, Eamon en
dc.contributor.author Murphy, Andrew W. en
dc.contributor.author Byrne, Mary C. en
dc.contributor.author Byrne, Molly en
dc.date.accessioned 2011-07-29T15:51:52Z en
dc.date.available 2011-07-29T15:51:52Z en
dc.date.issued 2010 en
dc.identifier.citation Gillespie,P., O'Shea,E., Murphy, A. W., Byrne,M. C., Byrne, M. "The cost-effectiveness of the SPHERE intervention for the secondary prevention of coronary heart disease" International Journal of Technology Assessment in Health Care (2010), 26: 263-271 en
dc.identifier.uri http://hdl.handle.net/10379/2103 en
dc.description.abstract Objectives: The Secondary Prevention of Heart disEase in geneRal practicE (SPHERE) trial has recently reported. This study examines the cost-effectiveness of the SPHERE intervention in both healthcare systems on the island of Ireland. Methods: Incremental cost-effectiveness analysis. A probabilistic model was developed to combine within-trial and beyond-trial impacts of treatment to estimate the lifetime costs and benefits of two secondary prevention strategies: Intervention - tailored practice and patient care plans; and Control - standardized usual care. Results: The intervention strategy resulted in mean cost savings per patient of -512.77 (95 percent confidence interval [CI], -1086.46-91.98) and an increase in mean quality-adjusted life-years (QALYs) per patient of 0.0051 (95 percent CI, -0.0101-0.0200), when compared with the control strategy. The probability of the intervention being cost-effective was 94 percent if decision makers are willing to pay -45,000 per additional QALY. Conclusions: Decision makers in both settings must determine whether the level of evidence presented is sufficient to justify the adoption of the SPHERE intervention in clinical practice. en
dc.format application/pdf en
dc.language.iso en en
dc.publisher Cambridge University Press en
dc.subject Coronary heart disease en
dc.subject Secondary prevention en
dc.subject General practice en
dc.subject Cost-effectiveness analysis en
dc.subject Irish Centre for Social Gerontology en
dc.title The cost-effectiveness of the SPHERE intervention for the secondary prevention of coronary heart disease en
dc.type Article en
dc.description.peer-reviewed peer-reviewed en

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