Browsing College of Engineering and Informatics by Author "Quinlan, Nathan J."
Now showing items 1-20 of 23
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Analysis of shear-induced platelet aggregation and breakup
Hellmuth, Rudolf; Bruzzi, Mark S.; Quinlan, Nathan J. (Springer, 2015-07-31)To better understand the mechanisms leading to the formation of thrombi of hazardous sizes in the bulk of the blood, we have developed a kinetic model of shear-induced platelet aggregation (SIPA). In our model, shear rate ... -
Application of the meshless finite volume particle method to flow-induced motion of a rigid body
Nestor, Ruairi M.; Quinlan, Nathan J. (ScienceDirect, 2013-10-01)We present a new approach to numerical modelling of incompressible flow of fluid about an elastically mounted rigid structure with large body motions. The solution is based on the Finite Volume Particle Method (FVPM), a ... -
Comment on "Prosthetic heart valves' mechanical loading of red blood cells in patients with hereditary membrane defects'', Grigioni et al.
Quinlan, Nathan J. (Elsevier, 2006-08-17) -
Development of the meshless finite volume particle method with exact and efficient calculation of interparticle area
Quinlan, Nathan J.; Lobovsky, Libor; Nestor, Ruairi M. (Elsevier, 2014-02-18)The Finite Volume Particle Method (FVPM) is a meshless method based on a definition of interparticle area which is closely analogous to cell face area in the classical finite volume method. In previous work, the interparticle ... -
Effect of eddy length scale on mechanical loading of blood cells in turbulent flow
Dooley, Patrick N.; Quinlan, Nathan J. (2009)Non-physiological turbulent blood flow is known to occur in and near implanted cardiovascular devices, but its effects on blood are poorly understood. The objective of this work is to investigate the effect of turbulent ... -
Extension of the finite volume particle method to viscous flow
Nestor, Ruairi M.; Basa, Mihai; Lastiwka, Martin; Quinlan, Nathan J. (Elsevier, 2009-03-20)The finite volume particle method (FVPM) is a mesh-free method for fluid dynamics which allows simple and accurate implementation of boundary conditions and retains the conservation and consistency properties of classical ... -
Extensions of the meshless finite volume particle method (FVPM) for static and dynamic free-surface flows
Quinlan, Nathan J. (Elsevier, 2018-10-04)The Finite Volume Particle Method (FVPM) is a meshless method that incorporates features of both Smoothed Particle Hydrodynamics and the Finite Volume Method. Here, two new formulations are presented which enhance its ... -
Fluid dynamics of gas exchange in high-frequency oscillatory ventilation: In vitro investigations in idealized and anatomically realistic airway bifurcation models
Heraty, Kevin B.; Laffey, John G.; Quinlan, Nathan J. (Springer, 2008-11)The objective of this work is to develop understanding of the local fluid dynamic mechanisms that underpin gas exchange in high-frequency oscillatory ventilation (HFOV). The flow field during HFOV was investigated ... -
High-resolution measurement of the unsteady velocity field to evaluate blood damage induced by a mechanical heart valve
Bellofiore, Alessandro; Quinlan, Nathan J. (Springer, 2011-09)We investigate the potential of prosthetic heart valves to generate abnormal flow and stress patterns, which can contribute to platelet activation and lysis according to blood damage accumulation mechanisms. High-resolution ... -
High-resolution measurements of leakage flow inside the hinge of a large-scale bileaflet mechanical heart valve hinge model
Klusak, Ewa; Quinlan, Nathan J. (Springer, 2019-06-24)Purpose It is believed that non-physiological leakage flow through hinge gaps during diastole contributes to thrombus formation in Bileaflet Mechanical Heart Valves (BMHVs). Because of the small scale and difficulty of ... -
Incompressible moving boundary flows with the finite volume particle method
Quinlan, Nathan J.; Nestor, Ruairi M. (Elsevier, 2010-03-24)Mesh-free methods offer the potential for greatly simplified modeling of flow with moving walls and phase interfaces. The finite volume particle method (FVPM) is a mesh-free technique based on interparticle fluxes which ... -
Measurement of cardiovascular device flow at scales approaching cell size
Bellofiore, Alessandro; Quinlan, Nathan J. (2009-09-24) -
Microscale flow structures measured downstream of a mechanical heart valve
Bellofiore, Alessandro; Quinlan, Nathan J. (Trinity College Dublin, 2010-01-22) -
A model for surface tension in the finite volume particle method without parasitic current
Moghimi, Mohsen H.; Quinlan, Nathan J. (NUI Galway, 2018-06-26)A surface tension model has been developed in the finite volume particle method (FVPM). Surface tension force is applied only on free-surface particles, which are inexpensively and robustly detected using the FVPM ... -
A model for surface tension in the meshless finite volume particle method without spurious velocity
Moghimi, Mohsen H.; Quinlan, Nathan J. (Elsevier, 2018-11-22)A surface tension model has been developed in the finite volume particle method (FVPM). FVPM is a conservative, consistent, meshless particle method that incorporates properties of both smoothed particle hydrodynamics and ... -
Models of flow-induced loading on blood cells in laminar and turbulent flow, with application to cardiovascular device flow
Quinlan, Nathan J.; Dooley, Patrick N. (Springer, 2007-08)Viscous shear stress and Reynolds stress are often used to predict hemolysis and thrombosis due to flow-induced stress on blood elements in cardiovascular devices. These macroscopic stresses are distinct from the true ... -
Particle transport velocity correction for complex boundaries in the Finite Volume Particle Method
McLoone, Maryrose; Moghimi, Mohsen H.; Quinlan, Nathan J. (NUI Galway, 2018-06-26)Particle methods such as smoothed particle hydrodynamics (SPH) and the finite volume particle method (FVPM) can suffer from strongly non-uniform and anisotropic particle distributions when purely Lagrangian particle ... -
Permeable and Non-reflecting Boundary Conditions in SPH
Lastiwka, Martin; Basa, Mihai; Quinlan, Nathan J. (Wiley, 2009-11)Inflow and outflow boundary conditions are essential for the application of computational fluid dynamics to many engineering scenarios. In this paper we present a new boundary condition implementation that enables the ... -
Robustness and accuracy of SPH formulations for viscous flow
Quinlan, Nathan J.; Lastiwka, Martin; Basa, Mihai (2009)Numerous methods are available for the modelling of viscous stress terms in smoothed particle hydrodynamics (SPH). In this work, the existing methods are investigated systematically and evaluated for a range of Reynolds ... -
Scale-up of an unsteady flow field for enhanced spatial and temporal resolution of PIV measurements: application to leaflet wake flow in a mechanical heart valve
Bellofiore, Alessandro; Donohue, Eilis M.; Quinlan, Nathan J. (Springer, 2011-07)A scale-up approach is developed to enhance effective spatial and temporal resolution of PIV measurements. An analysis shows that complete similarity can be maintained for certain unsteady flows and that all types of error ...