Browsing University of Galway Theses (PhD Theses) by Subject "rDNA"
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The genomic architecture of nucleolar organiser regions on the short arms of human acrocentric chromosomes
(2015-09-29)Nucleolar Organiser Regions (NORs) are comprised of ribosomal gene (rDNA) arrays and adjacent sequences. Nucleoli, the sites of ribosome biogenesis and key regulators of cellular growth and proliferation, form around NORs. ... -
Organisation and function of the Nucleolar Organiser Regions in human chromosomes.
(2013-12-20)The short-arms of the five acrocentric human chromosomes contain sequences that direct the assembly and function of the nucleolus, one of the key functional domains of the nucleus and ribosomal biogenesis, yet they are ...