Browsing University of Galway Theses (PhD Theses) by Author "Woods, Robert J"
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Computational design of glycomimetic inhibitors of Influenza A Adhesion
Smith, Hannah Mary Kate (2015-02-16)Many pathogens, such as avian influenza, Helicobacter pylori and Streptococcus pneumoniae, employ cell-surface glycans which terminate in Neu5AcAlpha(2-3)Gal as their adhesion partner.[1] As a result, a glycomimetic ... -
Expression, purification and characterization of carbohydrate-binding proteins
Murphy, Valerie (2014-05-29)Glycans play important roles in many biological interactions. They are involved in cell-cell interactions, function as a point of entry for viral infections and facilitate the adhesion of microbes in the body. Glycans of ... -
N- and O- linked Glycosylation, Developing Mass Spectrometric Strategies for the Characterisation of Glyco-epitopes
Kenny, Diarmuid T (2012-12-10)The overall goal of this thesis was to adopt a liquid chromatography-mass spectrometry (LC-MS) platform for glycomic analysis of glycoproteins. In particular we were interested in characterizing complex glycomic samples ...