Browsing University of Galway Theses (PhD Theses) by Author "Newell, John"
Now showing items 1-8 of 8
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Bayesian imputation of right censored data in time-to-event studies
Moghaddam, Shirin (NUI Galway, 2018-03-20)In time-to-event studies subjects are followed until the event of interest has happened. Subjects who do not experience the event are referred to as censored. Due to censoring, methods of plotting individual survival ... -
Derivative Estimation in Noisy Data; an Additive Penalty P-Spline Approach
Simpkin, Andrew (2010-12-20)In many situations it is of primary interest to estimate the rate of change of the relationship between response and explanatory variables. In this thesis derivative estimation using spline smoothing is explored. A review ... -
Extending the linear mixed modelling framework for method comparison studies involving functional responses with applications in elite sports
Das, Kishor (NUI Galway, 2023-01-10)A method comparison study compares two or more different methods measuring some quantity of interest and the aim is to determine the level of agreement between the methods. Most of the methodological developments in this ... -
Extensions and Applications of Survival Trees in Medical Data
Alvarez-Iglesias, Alberto (2012-09-17)Survival trees are a non-parametric modeling strategy that can be included in the area of statistical modeling. These type of models can be used as an alternative to Cox proportional hazards models for the analysis of ... -
Integration of Genetic Biomarkers in Prognostic Models for Breast Cancer Survival
Wall, Deirdre (2014-01-08)The main aim of my PhD is to create a prognostic model for invasive breast cancer patients for disease recurrence and death. The data were collected retrospectively and are comprised of 647 invasive breast cancer patients ... -
A modified depth function for outlier detection in multivariate data with applications
Abedin, Md Jaynal (NUI Galway, 2020-09-24)Data Science is the new and exciting interdisciplinary response that has emerged as a consequence of the staggering amounts of data generated in many new forms from digital images to audio to text. It is an interdisciplinary ... -
A statistical decision support system incorporating personalised adaptive reference ranges for longitudinal monitoring in prostate cancer
Roshan Sangachin, Davood (NUI Galway, 2019-12-05)The overall aims of this thesis are to use modern approaches in Biostatistics to help clinicians diagnose Prostate Cancer (PCa) early, and treat effectively, and to help patients choose between treatment options. Biostatistics ... -
Translational statistics and dynamic nomograms
Jalali, Amirhossein (NUI Galway, 2018-03-21)Translational Medicine, within biomedical and public health research domains, is defined as the convergence of basic and clinical research with the aim to transfer knowledge on the benefits and risks of therapies. The ...