Browsing University of Galway Theses (PhD Theses) by Author "Griffin, Matthew"
Now showing items 1-4 of 4
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The effects of anti-TNFα antibody therapy on peripheral blood mononuclear cells in patients with inflammatory bowel disease
Slevin, Stephanie (2015-09-30)Monocytes, recently classified as CD14++CD16- (classical), CD14++CD16+ (intermediate) and CD14dimCD16++ (non-classical) are considered to play a role in the pathogenesis of inflammatory bowel diseases (IBD). Anti-tumor ... -
An investigation of the immunometabolic interactions of obesity
Dennedy, Michael Conall (2013-09-04)Human monocytes are classified as classical, intermediate and non-classical according to their surface expression of CD14 and CD16. They also represent precursors to atherogenic foam cells and macrophages in metabolically ... -
Phenotypic and functional heterogeneity of intermediate monocytes in healthy adults.
Connaughton, Eanna (2015-09-30)Human blood monocytes are currently classified into three subsets: CD14++CD16- “Classical”, CD14++CD16+ “Intermediate” and CD14+CD16++ “Non-Classical”. Distinct functional differences between Classical and Non-Classical ... -
Phenotypic and functional properties of HLA-DRhi intermediate monocytes in health and chronic kidney disease
Cormican, Sarah (NUI Galway, 2022-03-25)Chronic kidney disease (CKD) is a common condition, characteristed by reduced renal function and frequently associated with progressive loss of glomerular filtration, ultimately reaching end stage renal disease (ESRD). ...