Browsing University of Galway Theses (PhD Theses) by Author "Finn, David P."
Now showing items 1-4 of 4
-
The Effect of Pain on Cognitive Function: Preclinical and Clinical Investigations
Moriarty, Orla (2012-10-19)Chronic pain is associated with high social and economic costs due to its disabling physical and psychological effects. Despite some evidence that chronic pain negatively affects cognitive function, little is known about ... -
Exploration of the opioidergic system in the olfactory bulbectomized rat model of depression
McHugh, Kelly Louise (NUI Galway, 2020-02-27)In recent years, there has been renewed interest in targeting the central opioid system as a novel strategy for the treatment of psychiatric disorders such as depression, due to its involvement in the regulation of mood, ... -
Investigating the role of the endogenous cannabinoid system in emotional modulation of pain: neurochemical and molecular mechanisms
Olango, Weredeselam Menna (2012-03-24)Abstract Pain represents a major unmet clinical need and affects a large number of individuals worldwide. The modulation of pain by cognitive and emotional factors is now widely recognised. Increased understanding of the ... -
Investigation of sexual dimorphism in an animal model of neuropathic pain: role of the endocannabinoid system
Boullon, Laura (NUI Galway, 2023-05-15)Although the presence of sexual dimorphism in the symptomatology of neuropathic pain is well-established, the neurobiology underlying sex differences in pain processing and modulation remains unclear. Gonadal hormones ...