Browsing University of Galway Theses (PhD Theses) by Subject "Fear"
Now showing items 1-3 of 3
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Investigating the role of the endogenous cannabinoid system in emotional modulation of pain: neurochemical and molecular mechanisms
(2012-03-24)Abstract Pain represents a major unmet clinical need and affects a large number of individuals worldwide. The modulation of pain by cognitive and emotional factors is now widely recognised. Increased understanding of the ... -
Regulation of fear, anxiety and cognition in the presence or absence of pain by peroxisome proliferator-activated receptors
(NUI Galway, 2019-06-07)Fear/anxiety and pain modulate one another reciprocally, but the neurobiological mechanisms that underlie this interaction are not completely understood. Fear-conditioned analgesia (FCA) is pain suppression upon exposure ... -
The role of the endocannabinoid system in the emotional modulation of pain
(NUI Galway, 2018-09-06)Fear-conditioned analgesia (FCA) is the robust suppression of pain that occurs upon reexposure to a context previously paired with an aversive stimulus. FCA is mediated by activation of the descending inhibitory pain ...